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Protein Overview: CE35492

General Information:
Name(s) found: CE35492 [WormBase]
Description(s) found:
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  • WBGene00017552 locus:nep-7 status:Partially_confirmed UniProt:O16792 protein_id:CCD64729.1 [WormBase]
  • gi|71986879|ref|NP_494534.2| hypothetical protein F18A12.3 [Caenorhabditis elegans] [NCBI NR]
  • gi|34365968|gb|AAB66075.2| Hypothetical protein F18A12.3 [Caenorhabditis elegans] [NCBI NR]
  • [wormpep111.fasta]
  • Hypothetical protein F18A12.3 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE35492 WBGene00017552 peptidase status:Partially_confirmed TR:O16792 protein_id:AAB66075.2 [wormpep150.fasta]
  • 35492 WBGene00017552 peptidase status:Partially_confirmed TR:O16792 protein_id:AAB66075.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • peptidase status:Partially_confirmed TN:AAB66075 protein_id:AAB66075.2 [wormpep115.fasta.reversed]
  • CE35492 WBGene00017552 peptidase status:Partially_confirmed UniProt:O16792_CAEEL protein_id:AAB66075.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE35492 WBGene00017552 peptidase status:Partially_confirmed UniProt:O16792_CAEEL protein_id:AAB66075.2| [wormORF-contam.fasta]
  • F18A12.3 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE35492 WBGene00017552 peptidase status:Partially_confirmed UniProt:O16792 protein_id:AAB66075.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE35492 WBGene00017552 locus:nep-7 peptidase status:Partially_confirmed UniProt:O16792 protein_id:CCD64729.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE35492 WBGene00017552 locus:nep-7 status:Partially_confirmed UniProt:O16792 protein_id:CCD64729.1 [wormpep246-ecoli-contam.fasta]
  • NEPrilysin metallopeptidase family OS=Caenorhabditis elegans GN=nep-7 PE=4 SV=2 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 481 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    Biological Process: proteolysis [IEALink to PubMed article]
    Molecular Function: zinc ion binding [IEALink to PubMed article]
    neprilysin activity [IEALink to PubMed article]
    metallopeptidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNVEKMREKF SSPWIALNLL LLMVFLALVT VHIKMTVEVK PVKLDELLSN AADSRNLCES  60
   61 PDCITLSHEL LNYQDPSVDP CVDFFQHACG RFHEQSSVES RTQKKRYILQ KQIREFLHNN 120
  121 KTSTSKSENL MKLVFDKCEA LQKSQNTGYL QEVHEVFNDI KKIGAWPLLD KNWDESKFDL 180
  181 NEMLTNLVKL GATNFGLFQF NFLGLIMGNF VEIAPTEKSD VEEIQMVLDI LKGNGIEPDR 240
  241 EEISRELEEY SMLEKKLKIV KENETISLNL ILPDVRSVNF SGLIAEMSHP SRVSKLSGMI 300
  301 TPKIITNKHP LLFETNGTES LDAIIESTSN RTLANYLIFN YIQSSRDILT ETYENCEQKV 360
  361 EAIKVIIGYP DHFDPPGTLD KEFEHIDLDS TDSFYRISQK LHRLRTEQQM EFIAGETPIS 420
  421 PVENVLEVSA HYDPSKNALT FLAPFLDDPF FDTTYPDYAN LFLSGRIIAH EIGHSVDGTS 480
  481 L

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..95] MSA 2.19299 View MSA. No confident structure predictions are available.
    2 View Details [96..481] PSI-BLAST 67.522879 Neutral endopeptidase (neprilysin)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • catalytic activity
    		•  0.361128926739778 bayes_pls_golite062009
  • hydrolase activity
    		•  0.29183147920977 bayes_pls_golite062009
  • peptidase activity
    		•  0.23695590197447 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.0341081586881899 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle