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Protein Overview: wrs-1

General Information:
Name(s) found: wrs-1 / CE35140 [WormBase]
Description(s) found:
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  • WBGene00006945 locus:wars-1 status:Confirmed UniProt:G5EDY2 protein_id:CAB60439.2 [WormBase]
  • gi|72001474|ref|NP_507683.2| tryptophanyl (W) tRNA Synthetase family member (wrs-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|33300622|emb|CAB60439.2| C. elegans protein Y80D3A.1, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|33300482|emb|CAE17953.1| C. elegans protein Y80D3A.1, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|30962537|dbj|BAC76735.1| tryptophanyl-tRNA synthetase (cytosolic) [Caenorhabditis elegans] [NCBI NR]
  • [wormpep111.fasta]
  • Hypothetical protein Y80D3A.1 [Caenorhabditis elegans]gi|33300482|emb|CAE17953.1| Hypothetical protein Y80D3A.1 [Caenorhabditis elegans]gi|30962537|dbj|BAC76735.1| tryptophanyl-tRNA synthetase (cytosolic) [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE35140 WBGene00006945 locus:wrs-1 tryptophanyl-tRNA synthetase status:Confirmed TR:Q9U1R2 protein_id:CAB60439.2 [wormpep150.fasta]
  • 35140 WBGene00006945 locus:wrs-1 tryptophanyl-tRNA synthetase status:Confirmed TR:Q9U1R2 protein_id:CAB60439.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • locus:wrs-1 tryptophanyl-tRNA synthetase status:Confirmed TR:Q9U1R2 protein_id:CAB60439.2 [wormpep115.fasta.reversed]
  • CE35140 WBGene00006945 locus:wrs-1 tryptophanyl-tRNA synthetase status:Confirmed UniProt:Q9U1R2_CAEEL protein_id:CAE17953.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE35140 WBGene00006945 locus:wrs-1 tryptophanyl-tRNA synthetase status:Confirmed UniProt:Q9U1R2_CAEEL protein_id:CAE17953.1| [wormORF-contam.fasta]
  • Hypothetical protein Y80D3A.1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • tryptophanyl (W) tRNA Synthetase family member (wrs-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • tryptophanyl-tRNA synthetase (cytosolic) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE35140 WBGene00006945 locus:wrs-1 tryptophanyl-tRNA synthetase status:Confirmed UniProt:Q9U1R2 protein_id:CAE17953.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • CE35140 WBGene00006945 locus:wars-1 tryptophanyl-tRNA synthetase status:Confirmed UniProt:G5EDY2 protein_id:CAB60439.2 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE35140 WBGene00006945 locus:wars-1 status:Confirmed UniProt:G5EDY2 protein_id:CAB60439.2 [wormpep246-ecoli-contam.fasta]
  • Tryptophanyl(W) Amino-acyl tRNA Synthetase OS=Caenorhabditis elegans GN=wars-1 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 417 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: tRNA aminoacylation for protein translation [IEALink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    tryptophanyl-tRNA aminoacylation [IEALink to PubMed article]
    growth [IMPLink to PubMed article]
    translation [IEALink to PubMed article]
    Molecular Function: nucleotide binding [IEALink to PubMed article]
    ATP binding [IEALink to PubMed article]
    aminoacyl-tRNA ligase activity [IEALink to PubMed article]
    tryptophan-tRNA ligase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAPAEQVAA EIENLKVNGG AAGGGVQEDE EDRVTPWEVT TTKATGIDYD KLIVKFGCRK  60
   61 LDEEIIARFE RVTGHKASPM LRRGMFFAHR DLTAILDRKE QGKPFYLYTG RGASSGSLHL 120
  121 GHLVPFIFTK WLQEVFDVPL VIQMTDDEKF LWKDMKVDEA KKMARENMKD IISVGFDPTK 180
  181 TFIFNNFDYM CPPFYENIVK IWKVVNTNQA RAIFGFTPED CLGKAAFPAV EAAPCFASSF 240
  241 PQIFGKRNDI PCLIPCAIDQ DPFFRMTRDV APRLKASKPS LIFSTFLPAL TGAQTKMSAS 300
  301 EPNTCIFLSD TAKQIKNKIN KYAFSGGQQT VQEHREKGGN CDVDISYQFL RFFLDDDEKL 360
  361 AEIRENYTKG EMLSGELKAL ATQKVQEIVL EMQERRKLVT DETVEEFVKV RPLAYKY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..417] PSI-BLAST 119.0 crystal structure of human tryptophanyl-tRNA synthetase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming carbon-oxygen bonds
    		•  7.16276509815667 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.16276509815667 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.13957775963187 bayes_pls_golite062009
  • ligase activity
    		•  6.11211476973434 bayes_pls_golite062009
  • tryptophan-tRNA ligase activity
    		•  5.34430928486195 bayes_pls_golite062009
  • glutamate-tRNA ligase activity
    		•  2.63681738794687 bayes_pls_golite062009
  • catalytic activity
    		•  2.37674226834122 bayes_pls_golite062009
  • methionine-tRNA ligase activity
    		•  2.01261843164558 bayes_pls_golite062009
  • tyrosine-tRNA ligase activity
    		•  1.88984817882585 bayes_pls_golite062009
  • arginine-tRNA ligase activity
    		•  1.13743634264647 bayes_pls_golite062009
  • cysteine-tRNA ligase activity
    		•  0.844943947059557 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.625793556381714 bayes_pls_golite062009
  • binding
    		•  0.27454602748467 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.2293846471193 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.161799496958314 bayes_pls_golite062009
  • glutamine-tRNA ligase activity
    		•  0.118292082006187 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle