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Protein Overview: egl-5

General Information:
Name(s) found: egl-5 / CE34523 [WormBase]
Description(s) found:
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  • WBGene00001174 locus:egl-5 Homeobox protein egl-5 status:Confirmed UniProt:P17486 protein_id:CCD63640.1 [WormBase]
  • gi|71981533|ref|NP_001021167.1| EGg Laying defective family member (egl-5) [Caenorhabditis elegans] [NCBI NR]
  • gi|32453027|gb|AAP82660.1| Egg laying defective protein 5, isoform c [Caenorhabditis elegans] [NCBI NR]
  • [wormpep111.fasta]
  • Egg laying defective protein 5, isoform c [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE34523 WBGene00001174 locus:egl-5 status:Confirmed SW:P17486 protein_id:AAP82660.1 [wormpep150.fasta]
  • 34523 WBGene00001174 locus:egl-5 status:Predicted TR:Q7YZV2 protein_id:AAP82660.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • CE34523 WBGene00001174 locus:egl-5 status:Predicted TR:Q7YZV2 protein_id:AAP82660.1 [wormpep132.fasta]
  • 34523 WBGene00001174 locus:egl-5 status:Confirmed SW:P17486 protein_id:AAP82660.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • CE34523 WBGene00001174 locus:egl-5 status:Confirmed TR:Q7YZV2 protein_id:AAP82660.1 [WormBase_C-elegans_na_01-20-2005_combined_reversed.fasta]
  • locus:egl-5 status:Partially_confirmed TR:Q7YZV2 protein_id:AAP82660.1 [wormpep115.fasta.reversed]
  • CE34523 WBGene00001174 locus:egl-5 status:Confirmed UniProt:P17486 protein_id:AAP82660.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE34523 WBGene00001174 locus:egl-5 status:Confirmed UniProt:P17486 protein_id:AAP82660.1| [wormORF-contam.fasta]
  • EGg Laying defective family member (egl-5) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE34523 WBGene00001174 locus:egl-5 status:Confirmed UniProt:P17486 protein_id:CCD63640.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE34523 WBGene00001174 locus:egl-5 status:Confirmed UniProt:P17486 protein_id:CCD63640.1 Homeobox protein egl-5 [wormpep246-ecoli-contam.fasta]
  • Isoform of P17486, Isoform c of Homeobox protein egl-5 OS=Caenorhabditis elegans GN=egl-5 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 222 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article][ISSLink to PubMed article]
    Biological Process: negative regulation of transcription from RNA polymerase II promoter [IMPLink to PubMed article]
    anterior/posterior pattern formation [IMPLink to PubMed article]
    tail tip morphogenesis [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    oviposition [IMPLink to PubMed article]
    regulation of cell adhesion [IMPLink to PubMed article]
    Molecular Function: transcription factor activity [IEALink to PubMed article]
    transcription regulator activity [ISSLink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTSTSAFDF GSSTASSAAT STTSSQPDAN DHLSRLAAMT QGVGKEDPET SSTPSTEASL  60
   61 YPVSAAYMQS YGWPQNYNYF GQPLGPATFP GWPQCYPNTA WPNYGELFAS SKKGRQTYQR 120
  121 YQTSVLEAKF QQSSYVSKKQ REELRLQTQL TDRQIKIWFQ NRRMKAKKEK QRVDDHTEHT 180
  181 PLLPANPPKG MGMDMDDEKK WQMAHWPPAA AHNPYQYPLC PP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..92] deduced N/A No confident structure predictions are available.
    2 View Details [93..222] PSI-BLAST 25.154902 Ultrabithorax (ubx) homeodomain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  3.57523737355937 bayes_pls_golite062009
  • DNA binding
    		•  3.00143272905695 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.89825020286436 bayes_pls_golite062009
  • transcription factor activity
    		•  2.53664874743748 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.84054423341798 bayes_pls_golite062009
  • binding
    		•  1.68817361068715 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.14821760889085 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.46503550280898 bayes_pls_golite062009
  • protein binding
    		•  0.111941607625758 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle