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Protein Overview: unc-62

General Information:
Name(s) found: unc-62 / CE33584 [WormBase]
Description(s) found:
Found 22 descriptions.
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  • WBGene00006796 locus:unc-62 Homeobox protein unc-62 status:Confirmed UniProt:Q9N5D6 protein_id:CCD72265.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 523 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: oocyte construction [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    oviposition [IMPLink to PubMed articleLink to PubMed article]
    cell migration [IMPLink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed article]
    Molecular Function: transcription factor activity [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQRQFNDGY GPPPGSASAD PASYIADPAA FYNLYTNMGG APTSTPMMHH EMGEAMKRDK  60
   61 ESIYAHPLYP LLVLLFEKCE LATSTPRDTS RDGSTSSDVC SSASFKDDLN EFVRHTQENA 120
  121 DKQYYVPNPQ LDQIMLQSIQ MLRFHLLELE KVHELCDNFC NRYVVCLKGK MPLDIVGDER 180
  181 ASSSQPPMSP GSMGHLGHSS SPSMAGGATP MHYPPPYEPQ SVPLPENAGV MGGHPMEGSS 240
  241 MAYSMAGMAA AAASSSSSSN QAGDHPLANG GTLHSTAGAS QTLLPIAVSS PSTCSSGGLR 300
  301 QDSTPLSGET PMGHANGNSM DSISEAAPSS ASSSSSSKNK PSTPNGGRIG KSRGRGIFPK 360
  361 QATNRLRQWL FQNLTHPYPS EEQKKQLAKE TGLTILQVNN WFINARRRIV QPMIDQNNRA 420
  421 GRSGQMNVCK NRRRNRSEQS PGPSPDSGSD SGANYSPDPS SLAASTAMPY PAEFYMQRTM 480
  481 PYGGFPSFTN PAMPFMNPMM GFQVAPTVDA LSQQWVDLSA PHE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..206] MSA 5.205976 View MSA. No confident structure predictions are available.
    2 View Details [207..334] deduced N/A No confident structure predictions are available.
    3 View Details [335..429] PSI-BLAST 11.69897 Solution structure of the homeobox domain of human homeobox protein PKNOX1
    4 View Details [430..523] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • transcription regulator activity
    		•  1.62959077995642 bayes_pls_golite062009
  • binding
    		•  1.48969201384255 bayes_pls_golite062009
  • DNA binding
    		•  1.2137926921894 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.02805703044131 bayes_pls_golite062009
  • transcription factor activity
    		•  0.89626527070971 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.06790788268651 bayes_pls_golite062009
  • protein binding
    		•  0.012115247005138 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle