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Protein Overview: CE32929

General Information:
Name(s) found: CE32929 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00011510 locus:pdha-1 status:Confirmed UniProt:Q8I111 protein_id:CAD59156.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 414 amino acids

    Gene Ontology:
    Cellular Component: intracellular membrane-bounded organelle [IEALink to PubMed article]
    Biological Process: oocyte construction [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    metabolic process [IEALink to PubMed article]
    Molecular Function: oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKFLSLVHL ERIWSTAMSL FARQLQSLTA SGIRTQQVRL ASTEVSFHTK PCKLHKLDNG  60
   61 PNTSVTLNRE DALKYYRDMQ VIRRMESAAG NLYKEKKIRG FCHLYSGQEA CAVGMKAAMT 120
  121 EGDAVITAYR CHGWTWLLGA TVTEVLAELT GRVAGNVHGK GGSMHMYTKN FYGGNGIVGA 180
  181 QQPLGAGVAL AMKYREQKNV CVTLYGDGAA NQGQLFEATN MAKLWDLPVL FVCENNGFGM 240
  241 GTTAERSSAS TEYYTRGDYV PGIWVDGMDI LAVREATKWA KEYCDSGKGP LMMEMATYRY 300
  301 HGHSMSDPGT SYRTREEIQE VRKTRDPITG FKDRIITSSL ATEEELKAID KEVRKEVDEA 360
  361 LKIATSDGVL PPEALYADIY HNTPAQEIRG ATIDETIVQP FKTSADVLKS IGRA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..414] PSI-BLAST 92.154902 E1-beta subunit of pyruvate dehydrogenase (PP module)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • pyruvate dehydrogenase activity
    		•  11.3856674722026 bayes_pls_golite062009
  • pyruvate dehydrogenase (acetyl-transferring) activity
    		•  11.0549577473177 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
    		•  10.8180381281695 bayes_pls_golite062009
  • 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity
    		•  7.00951713446616 bayes_pls_golite062009
  • alpha-ketoacid dehydrogenase activity
    		•  6.25236550086321 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  4.89064211833637 bayes_pls_golite062009
  • acetolactate synthase activity
    		•  4.51986503762195 bayes_pls_golite062009
  • transferase activity, transferring aldehyde or ketonic groups
    		•  3.8269109174531 bayes_pls_golite062009
  • 2-oxoisovalerate dehydrogenase (acylating) activity
    		•  3.00128844859152 bayes_pls_golite062009
  • cyclin-dependent protein kinase 5 activator regulator activity
    		•  3.00128844859152 bayes_pls_golite062009
  • catalytic activity
    		•  2.25537597692103 bayes_pls_golite062009
  • oxidoreductase activity
    		•  1.85833680148029 bayes_pls_golite062009
  • transketolase activity
    		•  1.53492491341322 bayes_pls_golite062009
  • protein binding
    		•  0.992849906276347 bayes_pls_golite062009
  • binding
    		•  0.750068469698571 bayes_pls_golite062009
  • transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
    		•  0.667418924427388 bayes_pls_golite062009
  • pyruvate decarboxylase activity
    		•  0.198062360371269 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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