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Protein Overview: oct-2

General Information:
Name(s) found: oct-2 / CE31675 [WormBase]
Description(s) found:
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  • WBGene00003843 locus:oct-2 status:Confirmed UniProt:Q23501 protein_id:CAA91492.4 [WormBase]
  • gi|72003720|ref|NP_509899.3| Organic Cation Transporter family member (oct-2) [Caenorhabditis elegans] [NCBI NR]
  • gi|22265949|emb|CAA91492.4| C. elegans protein ZK455.8a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • [wormpep88.fasta]
  • Hypothetical protein ZK455.8a [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE31675 WBGene00013977 membrane transporter status:Confirmed TR:Q23501 protein_id:CAA91492.4 [wormpep150.fasta]
  • 31675 WBGene00013977 membrane transporter status:Partially_confirmed TR:Q23501 protein_id:CAA91492.4 [wormpep130-phg-ecoli-orf-rand.fasta]
  • CE31675 WBGene00013977 membrane transporter status:Partially_confirmed TR:Q23501 protein_id:CAA91492.4 [wormpep132.fasta]
  • 31675 WBGene00013977 membrane transporter status:Confirmed TR:Q23501 protein_id:CAA91492.4 [wormpep150-phg-orf-ecoli-rand.fasta]
  • membrane transporter status:Partially_confirmed TR:Q23501 protein_id:CAA91492.4 [wormpep115.fasta.reversed]
  • CE31675 WBGene00003843 locus:oct-2 membrane transporter status:Confirmed UniProt:Q23501_CAEEL protein_id:CAA91492.4 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE31675 WBGene00003843 locus:oct-2 membrane transporter status:Confirmed UniProt:Q23501_CAEEL protein_id:CAA91492.4| [wormORF-contam.fasta]
  • ZK455.8a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE31675 WBGene00003843 locus:oct-2 membrane transporter status:Confirmed TR:Q23501 protein_id:CAA91492.4 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE31675 WBGene00003843 locus:oct-2 membrane transporter status:Confirmed UniProt:Q23501 protein_id:CAA91492.4 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • CE31675 WBGene00003843 locus:oct-2 status:Confirmed UniProt:Q23501 protein_id:CAA91492.4 [wormpep246-ecoli-contam.fasta]
  • Organic Cation Transporter OS=Caenorhabditis elegans GN=oct-2 PE=1 SV=4 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 757 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: ion transport [IEALink to PubMed article]
    drug transport [IEALink to PubMed article]
    phosphate transport [IEALink to PubMed article]
    carbohydrate transport [IEALink to PubMed article]
    transport [IEALink to PubMed article]
    Molecular Function: inorganic phosphate transmembrane transporter activity [IEALink to PubMed article]
    carbohydrate transmembrane transporter activity [IEALink to PubMed article]
    ion transmembrane transporter activity [IEALink to PubMed article]
    sugar:hydrogen symporter activity [IEALink to PubMed article]
    transporter activity [IEALink to PubMed article]
    drug transmembrane transporter activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEQVSSDEP PTEEQELDKE TEVKDDSLPH TLNIENHAVK QPFLASTHLP IRSETDLISN  60
   61 ISASSMMPLE NHPLIYSNPE FTTVRFLTPQ ASVQTVNAGA ASVAPSEASV NAENSRKPSK 120
  121 ARLQSEMEIR NQHYQKQKQY ASTKETRAKR LTDIDFEGIL QLIGGCSYWQ IIVYLIISVQ 180
  181 QVPHAMFNLS VVYMMYQPDH WCKIPFFNEE SFSAELGYTN YTWDQVLNST IAFPRTFNKQ 240
  241 RNELHHDQCH YFERDYVHIK LSPWAQVKDM NATGKINRCK EWEYDTSVMD RTIVTEWNRV 300
  301 CDNNWSRAHV HMSYSLGYLV GCFVGGFISD RYGRKTAITG FGILTMLFGF LLTYSKEFEI 360
  361 FLVVRFLLAA TNEAADLAAY VLCMEVTGTK YRSIVGSLIQ APWACGYAFL ALIAYLTKSW 420
  421 TMIHLICVLL HIISLMLLYF LPESPRWLIL NNKTKQAEKI IREACHYNKS RLPSDLGLVR 480
  481 HAEKKKWMKH NEKPSYFHLF RSSELRFRNV VLFIVWIATA LVYYGMVIAL SDQSSPGRRV 540
  541 FDGNFFLNNA MAGAIELPTL VFCVFLLRMG RKRSQMLVLF GSGLFLLTSV VMVYRKQSTL 600
  601 ALIFMLLSKA CIQGSFNILY IFTSELNPTV VRNSAVGISS MVARMGAGAS GYIAILSDVT 660
  661 MPLVPMTIFA CFSLLAGCLV LLLPETQGLP LPDTILDSVQ MVKRNTKPCG TLSGTFLGGI 720
  721 DDDAQPYGGK LPPRVSSDDE EEEEEEDSEE SIPEKTA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..139] PSI-BLAST 11.221849 No description for 2v3sA was found.
    2 View Details [140..258] deduced N/A No confident structure predictions are available.
    3 View Details [259..757] PSI-BLAST 33.69897 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • substrate-specific transmembrane transporter activity
    		•  5.46247398538901 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.58978526526921 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.31967711223954 bayes_pls_golite062009
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  3.94605227012838 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • organic anion transmembrane transporter activity
    		•  3.3413526350788 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  3.21476253433572 bayes_pls_golite062009
  • hexose phosphate transmembrane transporter activity
    		•  2.87308506088228 bayes_pls_golite062009
  • glucose-6-phosphate transmembrane transporter activity
    		•  2.87308506088228 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  2.15783210522667 bayes_pls_golite062009
  • binding
    		•  1.89539096965643 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • phosphate transmembrane transporter activity
    		•  1.47932844880848 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  0.143419068761182 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  0.143419068761182 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle