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View Structure Prediction Details

Protein: oct-2
Organism: Caenorhabditis elegans
Length: 757 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for oct-2.

Description E-value Query
Range
Subject
Range
CE31676 - WBGene00013977 status:Confirmed TR:Q95ZI5 protein_id:CAC42386.2
523.0 [0..1] [695..1]

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Predicted Domain #1
Region A:
Residues: [1-139]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEQVSSDEP PTEEQELDKE TEVKDDSLPH TLNIENHAVK QPFLASTHLP IRSETDLISN  60
   61 ISASSMMPLE NHPLIYSNPE FTTVRFLTPQ ASVQTVNAGA ASVAPSEASV NAENSRKPSK 120
  121 ARLQSEMEIR NQHYQKQKQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.221849
Match: 2v3sA
Description: No description for 2v3sA was found.

Predicted Domain #2
Region A:
Residues: [140-258]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YASTKETRAK RLTDIDFEGI LQLIGGCSYW QIIVYLIISV QQVPHAMFNL SVVYMMYQPD  60
   61 HWCKIPFFNE ESFSAELGYT NYTWDQVLNS TIAFPRTFNK QRNELHHDQC HYFERDYVH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [259-757]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IKLSPWAQVK DMNATGKINR CKEWEYDTSV MDRTIVTEWN RVCDNNWSRA HVHMSYSLGY  60
   61 LVGCFVGGFI SDRYGRKTAI TGFGILTMLF GFLLTYSKEF EIFLVVRFLL AATNEAADLA 120
  121 AYVLCMEVTG TKYRSIVGSL IQAPWACGYA FLALIAYLTK SWTMIHLICV LLHIISLMLL 180
  181 YFLPESPRWL ILNNKTKQAE KIIREACHYN KSRLPSDLGL VRHAEKKKWM KHNEKPSYFH 240
  241 LFRSSELRFR NVVLFIVWIA TALVYYGMVI ALSDQSSPGR RVFDGNFFLN NAMAGAIELP 300
  301 TLVFCVFLLR MGRKRSQMLV LFGSGLFLLT SVVMVYRKQS TLALIFMLLS KACIQGSFNI 360
  361 LYIFTSELNP TVVRNSAVGI SSMVARMGAG ASGYIAILSD VTMPLVPMTI FACFSLLAGC 420
  421 LVLLLPETQG LPLPDTILDS VQMVKRNTKP CGTLSGTFLG GIDDDAQPYG GKLPPRVSSD 480
  481 DEEEEEEEDS EESIPEKTA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.69897
Match: 1pw4A
Description: Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
substrate-specific transmembrane transporter activity 5.46247398538901 bayes_pls_golite062009
ion transmembrane transporter activity 4.58978526526921 bayes_pls_golite062009
cation transmembrane transporter activity 4.31967711223954 bayes_pls_golite062009
transporter activity 4.09176719149278 bayes_pls_golite062009
anion transmembrane transporter activity 3.94605227012838 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
organic anion transmembrane transporter activity 3.3413526350788 bayes_pls_golite062009
inorganic anion transmembrane transporter activity 3.21476253433572 bayes_pls_golite062009
hexose phosphate transmembrane transporter activity 2.87308506088228 bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity 2.87308506088228 bayes_pls_golite062009
organic acid transmembrane transporter activity 2.15783210522667 bayes_pls_golite062009
binding 1.89539096965643 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
phosphate transmembrane transporter activity 1.47932844880848 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
polyol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.812001619402678 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009
cation:sugar symporter activity 0.143419068761182 bayes_pls_golite062009
sugar:hydrogen symporter activity 0.143419068761182 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle