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Protein Overview: tbx-7

General Information:
Name(s) found: tbx-7 / CE29639 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00006544 locus:tbx-7 Putative T-box protein 7 status:Confirmed UniProt:Q95PX3 protein_id:CCD70953.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 327 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article][ISSLink to PubMed article]
    transcription factor complex [ISSLink to PubMed article]
    Biological Process: regulation of transcription, DNA-dependent [IEALink to PubMed article]
    regulation of transcription from RNA polymerase II promoter [ISSLink to PubMed article]
    Molecular Function: transcription factor activity [IEALink to PubMed article]
    RNA polymerase II transcription factor activity, enhancer binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEGYGRSLF SEKHFPHDRQ LLPPFTTTMS LGSFFSFPAS SAFFDRKKDD GVIDNPNVEL  60
   61 VNRNLWSTFL ECGTEMIITK KGRRMFPLVK LKLSGLDKNS NYTIIMEMIS VDKLRYKFWN 120
  121 GNWIVAGVGE HHPLPTCFVH PQSPRSGEWW MTDGVDFKMA KLSNNPFNND GHIVLNSMHR 180
  181 YNPRFHIVRA DSSGQPILAS LKTFSFKETE FIAVTAYQND VVTKCKIDNN PFAKGFRNID 240
  241 TVRKRKMNQI ISTPPASEDE EPEVKRTKSE IEAVMFSDPK VPQMSLQLIS QWQEALLSTI 300
  301 VQIPITNQKS SSERKSGFGV VDLLGSS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..250] PSI-BLAST 80.69897 T-box protein 3, tbx3
    2 View Details [251..327] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  3.82913410895101 bayes_pls_golite062009
  • DNA binding
    		•  3.66817147088612 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.64801189357929 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.4281783503437 bayes_pls_golite062009
  • transcription factor activity
    		•  3.00834358271623 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.78676291654359 bayes_pls_golite062009
  • protein binding
    		•  2.61625563263605 bayes_pls_golite062009
  • transcription activator activity
    		•  2.550621891551 bayes_pls_golite062009
  • DNA strand annealing activity
    		•  1.17814334604363 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.03496325074066 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.90477390899557 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.67715424282347 bayes_pls_golite062009
  • chromatin binding
    		•  0.34201146905158 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.21694638611622 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.0889583851427092 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.59

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle