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Protein Overview: exos-4.2

General Information:
Name(s) found: exos-4.2 / CE30059 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00000202 locus:exos-4.2 status:Confirmed UniProt:Q9N4P9 protein_id:CCD72537.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 241 amino acids

    Gene Ontology:
    Cellular Component: exosome (RNase complex) [IEALink to PubMed article]
    Biological Process: RNA processing [IEALink to PubMed article]
    Molecular Function: 3'-5'-exoribonuclease activity [IEALink to PubMed article]
    RNA binding [IEALink to PubMed article]
    exoribonuclease activity, producing 5'-phosphomonoesters [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTTRSNLSI PLTHLARIDD DRMETDSEEH KRANTAFRPL CVKCGVFGAQ DGSGYAEFGN  60
   61 TRVLAQITGP DGDGKWEEDR AKITIELKGI EDSVKVAEYR AQLASAVSAV IFASKYPGKV 120
  121 IEIEITVLSD DGGVLSTALS AVTLAISHSG IENMGLMASV HVAMNSDGEC LTDPSTSESE 180
  181 GAIGGVTFAF VPNLGQTTCV DIYGRIPLKS TSSLLEFAKQ RACALVPTIH KAIVNSVRER 240
  241 K

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..241] PSI-BLAST 55.045757 Archaeal exosome core

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 3'-5'-exoribonuclease activity
    		•  2.16830676862423 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  1.94887328847363 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.90115575554186 bayes_pls_golite062009
  • exoribonuclease activity
    		•  1.90081280972069 bayes_pls_golite062009
  • structural molecule activity
    		•  1.69321127364043 bayes_pls_golite062009
  • RNA binding
    		•  1.36549953164096 bayes_pls_golite062009
  • ribonuclease activity
    		•  1.31550811238109 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.20748032530392 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.05662964529454 bayes_pls_golite062009
  • binding
    		•  0.907487229190259 bayes_pls_golite062009
  • catalytic activity
    		•  0.878454819018611 bayes_pls_golite062009
  • DNA binding
    		•  0.828609700556836 bayes_pls_golite062009
  • nuclease activity
    		•  0.69721312877891 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  0.477960254167 bayes_pls_golite062009
  • tRNA-specific ribonuclease activity
    		•  0.383567539949931 bayes_pls_golite062009
  • mRNA binding
    		•  0.17546516359584 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle