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View Structure Prediction Details

Protein: exos-4.2
Organism: Caenorhabditis elegans
Length: 241 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for exos-4.2.

Description E-value Query
Range
Subject
Range
PNP_CARHZ - Polyribonucleotide nucleotidyltransferase OS=Carboxydothermus hydrogenoformans (strain ATCC BAA-161 ...
248.0 [0..2] [239..298]

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Predicted Domain #1
Region A:
Residues: [1-241]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTTRSNLSI PLTHLARIDD DRMETDSEEH KRANTAFRPL CVKCGVFGAQ DGSGYAEFGN  60
   61 TRVLAQITGP DGDGKWEEDR AKITIELKGI EDSVKVAEYR AQLASAVSAV IFASKYPGKV 120
  121 IEIEITVLSD DGGVLSTALS AVTLAISHSG IENMGLMASV HVAMNSDGEC LTDPSTSESE 180
  181 GAIGGVTFAF VPNLGQTTCV DIYGRIPLKS TSSLLEFAKQ RACALVPTIH KAIVNSVRER 240
  241 K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.045757
Match: 2ba0F
Description: Archaeal exosome core
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
3'-5'-exoribonuclease activity 2.16830676862423 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 1.94887328847363 bayes_pls_golite062009
structural constituent of ribosome 1.90115575554186 bayes_pls_golite062009
exoribonuclease activity 1.90081280972069 bayes_pls_golite062009
structural molecule activity 1.69321127364043 bayes_pls_golite062009
RNA binding 1.36549953164096 bayes_pls_golite062009
ribonuclease activity 1.31550811238109 bayes_pls_golite062009
transcription regulator activity 1.20748032530392 bayes_pls_golite062009
nucleic acid binding 1.05662964529454 bayes_pls_golite062009
binding 0.907487229190259 bayes_pls_golite062009
catalytic activity 0.878454819018611 bayes_pls_golite062009
DNA binding 0.828609700556836 bayes_pls_golite062009
nuclease activity 0.69721312877891 bayes_pls_golite062009
3'-5' exonuclease activity 0.477960254167 bayes_pls_golite062009
tRNA-specific ribonuclease activity 0.383567539949931 bayes_pls_golite062009
mRNA binding 0.17546516359584 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle