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Protein Overview: CE29873

General Information:
Name(s) found: CE29873 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00012694 status:Confirmed UniProt:Q8MYM8 protein_id:CAD31828.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 263 amino acids

    Gene Ontology:
    Cellular Component: transcription factor TFIIF complex [IEALink to PubMed article]
    Biological Process: morphogenesis of an epithelium [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    transcription initiation from RNA polymerase II promoter [IEALink to PubMed article]
    Molecular Function: ATP binding [IEALink to PubMed article]
    RNA polymerase II transcription factor activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPTKRYSND VDCELAKRSI WLVKVPRYLS ELWDANEGNV VGKLQIGAQV ELHTAKGLIH  60
   61 PKPKEPTEGS SSTVTQPEAS EIPTEYSFIL HDVKSQTMSV LSEDKQGLGA DAPIKTGKLA 120
  121 IEGRIIKKAE CRPPATSKYM KMKLAHIVKN TQPKKTVKMI EKAAVKFKPV SVHAEDMIKS 180
  181 KQKKDGAKTY RADRDVLRGA LFKAFEKHSF YRLQDLQQLL QQPVSYVKEV LQEIAVYNTA 240
  241 PPHKSLWCLK PEYCNYKVNA QSE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..134] PSI-BLAST 33.69897 TFIIF beta subunit, Rap30
    2 View Details [135..263] PSI-BLAST 27.0 DNA-BINDING DOMAIN FROM HUMAN RAP30, NMR, MINIMIZED AVERAGE

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • general RNA polymerase II transcription factor activity
    		•  10.2797850053222 bayes_pls_golite062009
  • transcription initiation factor activity
    		•  6.22439849848084 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  4.06672086326535 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.89911747857156 bayes_pls_golite062009
  • binding
    		•  2.17316238057078 bayes_pls_golite062009
  • transcription activator activity
    		•  2.12958061949296 bayes_pls_golite062009
  • protein binding
    		•  1.90482509358938 bayes_pls_golite062009
  • transcription coactivator activity
    		•  1.30173573105398 bayes_pls_golite062009
  • transcription factor binding
    		•  0.677361513203971 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.43974291826617 bayes_pls_golite062009
  • catalytic activity
    		•  0.304516551414824 bayes_pls_golite062009
    2
    Term Confidence Notes
  • general RNA polymerase II transcription factor activity
    		•  5.67074370996647 bayes_pls_golite062009
  • transcription regulator activity
    		•  5.55329976718261 bayes_pls_golite062009
  • DNA binding
    		•  5.08959163553491 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.99681957904233 bayes_pls_golite062009
  • transcription factor activity
    		•  4.33152142980289 bayes_pls_golite062009
  • transcription activator activity
    		•  3.70589483230587 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  3.58179858678904 bayes_pls_golite062009
  • binding
    		•  3.52874320222492 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.60738445921725 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.22485867684613 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  1.82365519759474 bayes_pls_golite062009
  • RNA polymerase activity
    		•  1.82365519759474 bayes_pls_golite062009
  • transcription elongation regulator activity
    		•  1.81270943531115 bayes_pls_golite062009
  • protein binding
    		•  1.80415286835431 bayes_pls_golite062009
  • RNA binding
    		•  0.992043085614693 bayes_pls_golite062009
  • transcription factor binding
    		•  0.85714789329232 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.66743181561551 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.237727660028553 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  0.23177057841536 bayes_pls_golite062009
  • positive transcription elongation factor activity
    		•  0.13524243942225 bayes_pls_golite062009
  • structural molecule activity
    		•  0.111941063082739 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle