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Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules. A protein complex, distinct from RNA polymerase, that associates with DNA at promoters or at cis-acting regulatory sequences, by direct binding or by interaction with other DNA-binding polypeptides or complexes, and regulates transcription. Large protein complex composed of the RNA polymerase core complex and a variety of other proteins including transcription factor complexes TFIIA, D, E, F, and H which are required for promoter recognition, and the Mediator subcomplex. Catalyzes the synthesis of eukaryotic pre-mRNA. Any constituent part of the nucleoplasm, that part of the nuclear content other than the chromosomes or the nucleolus. A general transcription initiation factor which in humans consists of a heterodimer of an alpha and a beta subunit. Helps recruit RNA polymerase II to the initiation complex and promotes translation elongation.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: transcription factor TFIIF complex
Acc: GO:0005674
Aspect: Cellular Component
Desc: A general transcription initiation factor which in humans consists of a heterodimer of an alpha and a beta subunit. Helps recruit RNA polymerase II to the initiation complex and promotes translation elongation.
Proteins in PDR annotated with:
   This term: 20 [Search]
   Term or descendants: 20 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0005674 - transcription factor TFIIF complex (interactive image map)

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