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Protein Overview: ncbp-1

General Information:
Name(s) found: ncbp-1 / CE29793 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00018156 locus:ncbp-1 Nuclear cap-binding protein subunit 1 status:Confirmed UniProt:O01763 protein_id:CCD70767.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 798 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: collagen and cuticulin-based cuticle attachment to epithelium [IMPLink to PubMed article]
    RNA metabolic process [IEALink to PubMed article]
    locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    growth [IMPLink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: protein binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRRRQFDDE DEVQMKRRRG APLIEDVEKK LQGVIGKVGE NTGSSIECNL DKLTAFLHDD  60
   61 LEKYRASIID IIAGCAIYLP NRVTVYTTLV GLLNSKNFNF GGDVVEKLIS EQQDLLSKQK 120
  121 YQEAQNLAIF LCDLGNSGVL TAQSIGEYLE SFIAAAFEEN MPQVRNDYYI QTVLRCLPWI 180
  181 GKELTEKAPE QMENIGEAIG KYLELRNKNH VALLQVWREG STDQKQEDYL ESLSAQIEAL 240
  241 RNADWVENHI PRHYSGFETT LQDALQHNLP SFQSPEHTSD MIYPYPLVVF RLFQDADCSA 300
  301 FSSKPLPGDS SIDRFLFEGE IAWIIEKNQF NRKACARELL AFAEENPSVP IGFLIFETIF 360
  361 GQMLRLPHAP YPAIFHCSLV LELLKLKPDD YPQILVQTVE CIYRRADSMQ PVCIDRMVDW 420
  421 FSFHLSNFQY RYTWTDWKDC LNKDAFSGSQ IFVREVIEKC RRFGSYEKII AALPQDFVKI 480
  481 HPCSPEVRYL IDEEDTALVQ RAETFTQMFQ ERQPAEAFLN ELKSNDENDE LPYNINEFGL 540
  541 FVMVMLKMAS KTYSHNFSAL FRYQTTLKTV CDASELYQEK LLETLYSCWK TNQQMLMILT 600
  601 DKLLKMQVID CSAVVGWLFD EKMWQEHDRQ WLFEVLNQAL EKLTRQINVV EKDIKELTEK 660
  661 TENKIKEEDD EESDIKMDED ETKEEKFKQD LEDLENNKEK LERMVTFQKG LFNDFLIAFI 720
  721 EEIKNAATSN TSEMDGSGDT PGTQTPKFMW LRGRFCHVLL AHAETLLKHS SNIADEVFSE 780
  781 GTDPSIIECF NQFQSLRL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..798] PSI-BLAST 1000.0 CBP80, 80KDa nuclear cap-binding protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA cap binding
    		•  6.31996430626206 bayes_pls_golite062009
  • binding
    		•  3.0667965351474 bayes_pls_golite062009
  • protein binding
    		•  2.78733902345842 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.74745843355294 bayes_pls_golite062009
  • RNA binding
    		•  2.62683106046883 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.90912542848632 bayes_pls_golite062009
  • DNA binding
    		•  1.77040152722002 bayes_pls_golite062009
  • transcription activator activity
    		•  1.33885628961586 bayes_pls_golite062009
  • transcription factor activity
    		•  1.27944481949335 bayes_pls_golite062009
  • mRNA binding
    		•  1.24616647164637 bayes_pls_golite062009
  • RNA 7-methylguanosine cap binding
    		•  0.841392474686331 bayes_pls_golite062009
  • transcription factor binding
    		•  0.00210118982863072 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle