Protein Overview: pax-2

General Information:
Name(s) found:	pax-2 / CE29504 [WormBase]
Description(s) found: Found 19 descriptions. SHOW ALL	WBGene00003938 locus:pax-2 status:Partially_confirmed UniProt:Q21263 protein_id:CCD70278.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	351 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA]
Biological Process:	multicellular organismal development [IEA]
Molecular Function:	DNA binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFTKTFSNNY MTSSQSAYCN LQQYHDSRVC LLKCCRVQKV DPYFPRIALN SATSYPTVSG  60
   61 TVSLPKAETV EPDLWIKSFK GNEDPLLSDG SHTGVNQLGG VFVNGRPLPD TIRAQIVEMS 120
  121 QHGTRPCDIS RQLKVSHGCV SKILGRYYST GSVRPGVIGG SKPKVATPRV VECIAGYKRA 180
  181 NPTMFAWEIR QKLIEDQICG EENVPSVSSI NRIVRNKSFM AQLATPTSVT PSVARPSSAT 240
  241 SQNQRSPPRG VQQHMQQSTS VQQLQQFQLT SAATVNSLIS RPAFAIPGTT HSINGLLGTF 300
  301 PHSSLLDDKF TNLSTHSADM SLVYPTGLVG EHDWAMRTPM VILPQNYCGQ L

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..87]	deduced	N/A	No confident structure predictions are available.
2	View Details	[88..222]	PSI-BLAST	57.69897	Pax-5
3	View Details	[223..351]	PSI-BLAST	11.0	Paired protein

Functions predicted (by domain):

#

Gene Ontology predictions

1

No functions predicted.

2

Term	Confidence	Notes
transcription regulator activity	5.13863038737912	bayes_pls_golite062009
DNA binding	4.66369707598026	bayes_pls_golite062009
nucleic acid binding	4.51452285155271	bayes_pls_golite062009
transcription factor activity	4.06706589695599	bayes_pls_golite062009
sequence-specific DNA binding	3.5139760613123	bayes_pls_golite062009
RNA polymerase II transcription factor activity	3.16896789933192	bayes_pls_golite062009
transcription activator activity	3.10621734076555	bayes_pls_golite062009
binding	3.02779747447702	bayes_pls_golite062009
transcription repressor activity	1.91962622287073	bayes_pls_golite062009
protein binding	1.88087411289001	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	1.73068440195944	bayes_pls_golite062009
chromatin binding	1.68956710349366	bayes_pls_golite062009
transcription factor binding	1.40653841901929	bayes_pls_golite062009
transcription cofactor activity	0.84983974758882	bayes_pls_golite062009
transcription corepressor activity	0.25931464844298	bayes_pls_golite062009

3

Term	Confidence	Notes
transcription regulator activity	5.13863038737912	bayes_pls_golite062009
DNA binding	4.66369707598026	bayes_pls_golite062009
nucleic acid binding	4.51452285155271	bayes_pls_golite062009
transcription factor activity	4.06706589695599	bayes_pls_golite062009
sequence-specific DNA binding	3.5139760613123	bayes_pls_golite062009
RNA polymerase II transcription factor activity	3.16896789933192	bayes_pls_golite062009
transcription activator activity	3.10621734076555	bayes_pls_golite062009
binding	3.02779747447702	bayes_pls_golite062009
transcription repressor activity	1.91962622287073	bayes_pls_golite062009
protein binding	1.88087411289001	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	1.73068440195944	bayes_pls_golite062009
chromatin binding	1.68956710349366	bayes_pls_golite062009
transcription factor binding	1.40653841901929	bayes_pls_golite062009
transcription cofactor activity	0.84983974758882	bayes_pls_golite062009
transcription corepressor activity	0.25931464844298	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle