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Protein Overview: nas-25

General Information:
Name(s) found: nas-25 / CE28935 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00003544 locus:nas-25 Zinc metalloproteinase nas-25 status:Confirmed UniProt:Q20459 protein_id:CAA91045.3 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 399 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEALink to PubMed article]
    Biological Process: proteolysis [IEALink to PubMed article]
    Molecular Function: zinc ion binding [IEALink to PubMed article]
    astacin activity [IEALink to PubMed article]
    metallopeptidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQIYLGITIC LVAFLTVIDC AIPYYRTHSN FGSLGRRKVR QVQRDLTYRW PNNTVPYYVG  60
   61 NVTSTIKKSV RLAIEELQAW TCIRFQNVNE KYSDGDSVRI VDLGSCSSPI GRQQIGTQDV 120
  121 SLTKNCWGMG TAIHELMHAI GIEHTQSRSD RNRYLDILAQ NIDNRDLPNF ELLSPRLWAN 180
  181 LVPYDYGSVM HYSADSFSNK DDEQTMLPKD RSFIETMGSM IPNFYDFDQI NQYYQCYDSC 240
  241 RNAGQLANCA NGGIPNPNNC QVCNCPMGYG GDLCDQRPEG CGSTLVATDR WQKQKLSVRF 300
  301 SRNDDQYFTF CNSWIVGPSD RTLQVIYEIT SDSIRRQICS FGCYEGGIEV KHLQDPRITN 360
  361 DRDCCLNTPL NLTTTVNPLP VILYTSGATV TYDFSYRYV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..243] PSI-BLAST 33.522879 STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES
    2 View Details [244..399] PSI-BLAST 17.522879 Mannose-binding protein associated serine protease 2, MASP2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  0.361128926739778 bayes_pls_golite062009
  • hydrolase activity
    		•  0.29183147920977 bayes_pls_golite062009
  • peptidase activity
    		•  0.23695590197447 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.0341081586881899 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  0.286076792172079 bayes_pls_golite062009
  • protein binding
    		•  0.14494900666454 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle