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View Structure Prediction Details

Protein: nas-25
Organism: Caenorhabditis elegans
Length: 399 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nas-25.

Description E-value Query
Range
Subject
Range
gi|7512084, gi|1... - pir||S71352 metalloproteinase (EC 3.4.24.-) 10 precursor, blastula - sea urchin (Paracentrotus livid...
273.0 [0..16] [398..64]

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Predicted Domain #1
Region A:
Residues: [1-243]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQIYLGITIC LVAFLTVIDC AIPYYRTHSN FGSLGRRKVR QVQRDLTYRW PNNTVPYYVG  60
   61 NVTSTIKKSV RLAIEELQAW TCIRFQNVNE KYSDGDSVRI VDLGSCSSPI GRQQIGTQDV 120
  121 SLTKNCWGMG TAIHELMHAI GIEHTQSRSD RNRYLDILAQ NIDNRDLPNF ELLSPRLWAN 180
  181 LVPYDYGSVM HYSADSFSNK DDEQTMLPKD RSFIETMGSM IPNFYDFDQI NQYYQCYDSC 240
  241 RNA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.522879
Match: 1astA
Description: STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.361128926739778 bayes_pls_golite062009
hydrolase activity 0.29183147920977 bayes_pls_golite062009
peptidase activity 0.23695590197447 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 0.0341081586881899 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [244-399]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GQLANCANGG IPNPNNCQVC NCPMGYGGDL CDQRPEGCGS TLVATDRWQK QKLSVRFSRN  60
   61 DDQYFTFCNS WIVGPSDRTL QVIYEITSDS IRRQICSFGC YEGGIEVKHL QDPRITNDRD 120
  121 CCLNTPLNLT TTVNPLPVIL YTSGATVTYD FSYRYV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.522879
Match: 1nt0A
Description: Mannose-binding protein associated serine protease 2, MASP2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.286076792172079 bayes_pls_golite062009
protein binding 0.14494900666454 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle