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Protein Overview: kin-2

General Information:
Name(s) found: kin-2 / CE28749 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00002190 locus:kin-2 cAMP-dependent protein kinase regulatory subunit status:Partially_confirmed UniProt:P30625 protein_id:CCD67513.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 334 amino acids

    Gene Ontology:
    Cellular Component: cAMP-dependent protein kinase complex [IEALink to PubMed article]
    Biological Process: locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    signal transduction [IEALink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    protein amino acid phosphorylation [IEALink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed articleLink to PubMed article]
    growth [IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: cAMP-dependent protein kinase regulator activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGQQLSNRRN SQSVGATKNA KTPKPKEGGN PDAADDDDII VEPPKRSGGR RTGISAEPIK  60
   61 EDDTEYKKVV IPKDDATRRS LESAMRKNLL FAHLEEDEQK TMYDAMFPVE KSAGETIIEQ 120
  121 GEEGDNFYVI DKGTVDVYVN HEYVLTINEG GSFGELALIY GTPRAATVIA KTDVKLWAID 180
  181 RLTYRRILMG SVTKKRKMYD EFLSKVQILA DLDQWERANV ADALERCDFE PGTHVVEQGQ 240
  241 PGDEFFIILE GEANVLQKRS DDAPFDVVGH LGMSDYFGEI ALLLDRPRAA TVVAKTHLKC 300
  301 IKLDRNRFER VMGPVREILK RDVSNYNSYV KLMT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..334] PSI-BLAST 54.045757 REGULATORY SUBUNIT OF CAMP DEPENDENT PROTEIN KINASE

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cAMP-dependent protein kinase regulator activity
    		•  2.78017841119787 bayes_pls_golite062009
  • ion channel activity
    		•  2.31035709846974 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  2.27592163816493 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  2.26667533523982 bayes_pls_golite062009
  • channel activity
    		•  2.26667533523982 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  2.2092561065515 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  2.2092561065515 bayes_pls_golite062009
  • gated channel activity
    		•  2.18803972331121 bayes_pls_golite062009
  • cation channel activity
    		•  2.02552034972667 bayes_pls_golite062009
  • protein binding
    		•  1.86347494944834 bayes_pls_golite062009
  • binding
    		•  1.80151718402565 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.713762730241 bayes_pls_golite062009
  • protein kinase regulator activity
    		•  1.62310041223456 bayes_pls_golite062009
  • kinase regulator activity
    		•  1.532709858977 bayes_pls_golite062009
  • enzyme regulator activity
    		•  1.40720858109605 bayes_pls_golite062009
  • DNA binding
    		•  1.3674035196992 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.32134541762158 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  1.23047915537725 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  1.11752634454797 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.09750390509403 bayes_pls_golite062009
  • intracellular ligand-gated ion channel activity
    		•  0.998738492193644 bayes_pls_golite062009
  • transcription factor activity
    		•  0.957126529211267 bayes_pls_golite062009
  • GTPase regulator activity
    		•  0.930640481652164 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  0.910527807644534 bayes_pls_golite062009
  • transcription activator activity
    		•  0.908553387711064 bayes_pls_golite062009
  • guanyl-nucleotide exchange factor activity
    		•  0.848189810874263 bayes_pls_golite062009
  • cAMP binding
    		•  0.797267619017029 bayes_pls_golite062009
  • cyclic nucleotide binding
    		•  0.756298775192352 bayes_pls_golite062009
  • cyclic nucleotide-gated ion channel activity
    		•  0.744742680465958 bayes_pls_golite062009
  • intracellular cyclic nucleotide activated cation channel activity
    		•  0.744742680465958 bayes_pls_golite062009
  • cGMP binding
    		•  0.328747528349599 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle