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View Structure Prediction Details

Protein: kin-2
Organism: Caenorhabditis elegans
Length: 334 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for kin-2.

Description E-value Query
Range
Subject
Range
gi|39598139, gi|... - gi|39598139|emb|CAE68831.1| Hypothetical protein CBG14791 [Caenorhabditis briggsae], gi|187028145|em...
gi|157769977 - gi|157769977|ref|XP_001676809.1| Hypothetical protein CBG14791 [Caenorhabditis briggsae AF16]
232.0 [0..1] [334..1]

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Predicted Domain #1
Region A:
Residues: [1-334]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGQQLSNRRN SQSVGATKNA KTPKPKEGGN PDAADDDDII VEPPKRSGGR RTGISAEPIK  60
   61 EDDTEYKKVV IPKDDATRRS LESAMRKNLL FAHLEEDEQK TMYDAMFPVE KSAGETIIEQ 120
  121 GEEGDNFYVI DKGTVDVYVN HEYVLTINEG GSFGELALIY GTPRAATVIA KTDVKLWAID 180
  181 RLTYRRILMG SVTKKRKMYD EFLSKVQILA DLDQWERANV ADALERCDFE PGTHVVEQGQ 240
  241 PGDEFFIILE GEANVLQKRS DDAPFDVVGH LGMSDYFGEI ALLLDRPRAA TVVAKTHLKC 300
  301 IKLDRNRFER VMGPVREILK RDVSNYNSYV KLMT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 54.045757
Match: 1rgsA
Description: REGULATORY SUBUNIT OF CAMP DEPENDENT PROTEIN KINASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cAMP-dependent protein kinase regulator activity 2.78017841119787 bayes_pls_golite062009
ion channel activity 2.31035709846974 bayes_pls_golite062009
substrate-specific channel activity 2.27592163816493 bayes_pls_golite062009
passive transmembrane transporter activity 2.26667533523982 bayes_pls_golite062009
channel activity 2.26667533523982 bayes_pls_golite062009
ligand-gated channel activity 2.2092561065515 bayes_pls_golite062009
ligand-gated ion channel activity 2.2092561065515 bayes_pls_golite062009
gated channel activity 2.18803972331121 bayes_pls_golite062009
cation channel activity 2.02552034972667 bayes_pls_golite062009
protein binding 1.86347494944834 bayes_pls_golite062009
binding 1.80151718402565 bayes_pls_golite062009
transcription regulator activity 1.713762730241 bayes_pls_golite062009
protein kinase regulator activity 1.62310041223456 bayes_pls_golite062009
kinase regulator activity 1.532709858977 bayes_pls_golite062009
enzyme regulator activity 1.40720858109605 bayes_pls_golite062009
DNA binding 1.3674035196992 bayes_pls_golite062009
nucleic acid binding 1.32134541762158 bayes_pls_golite062009
ion transmembrane transporter activity 1.23047915537725 bayes_pls_golite062009
metal ion transmembrane transporter activity 1.11752634454797 bayes_pls_golite062009
cation transmembrane transporter activity 1.09750390509403 bayes_pls_golite062009
intracellular ligand-gated ion channel activity 0.998738492193644 bayes_pls_golite062009
transcription factor activity 0.957126529211267 bayes_pls_golite062009
GTPase regulator activity 0.930640481652164 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 0.910527807644534 bayes_pls_golite062009
transcription activator activity 0.908553387711064 bayes_pls_golite062009
guanyl-nucleotide exchange factor activity 0.848189810874263 bayes_pls_golite062009
cAMP binding 0.797267619017029 bayes_pls_golite062009
cyclic nucleotide binding 0.756298775192352 bayes_pls_golite062009
cyclic nucleotide-gated ion channel activity 0.744742680465958 bayes_pls_golite062009
intracellular cyclic nucleotide activated cation channel activity 0.744742680465958 bayes_pls_golite062009
cGMP binding 0.328747528349599 bayes_pls_golite062009

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