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Protein Overview: ceh-14

General Information:
Name(s) found: ceh-14 / CE28335 [WormBase]
Description(s) found:
Found 23 descriptions.
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  • WBGene00000438 locus:ceh-14 Homeobox protein ceh-14 status:Partially_confirmed UniProt:P20271 protein_id:CCD71294.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 351 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article][IEALink to PubMed article]
    Biological Process: thermosensory behavior [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    Molecular Function: transcription factor activity [IEALink to PubMed article][ISSLink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    protein binding [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLGHNILTLG ECDELDNHIV MCSTGLLSPQ EDFSNVNAGH PNNEEAICSL CDKKIRDRFV  60
   61 SKVNGRCYHS SCLRCSTCKD ELGATCFLRE DSMYCRAHFY KKFGTKCSSC NEGIVPDHVV 120
  121 RKASNHVYHV ECFQCFICKR SLETGEEFYL IADDARLVCK DDYEQARDKH CNELEGDGSN 180
  181 KRPRTTISAK SLETLKQAYQ TSSKPARHVR EQLASETGLD MRVVQVWFQN RRAKEKRLKK 240
  241 DAGRRWKSSN RAESDSNSPI ESINGQSPNY LYLDHPMDDG NESNYLFHSR EQTPDKYYRN 300
  301 ETPSTDPPPM HMTTPSVLTT NFSTPLSLST NVYNLPPPES QLIPHMTPQY I

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..157] PSI-BLAST 19.522879 No description for 2dfyX was found.
    2 View Details [158..241] PSI-BLAST 6.221849 Ultrabithorax (ubx) homeodomain
    3 View Details [242..351] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  2.71840976776163 bayes_pls_golite062009
  • DNA binding
    		•  2.61711182194361 bayes_pls_golite062009
  • binding
    		•  2.59102816487173 bayes_pls_golite062009
  • transcription factor activity
    		•  2.18905180070231 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.93681952439958 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.69885241317809 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.35613772918036 bayes_pls_golite062009
  • transcription activator activity
    		•  0.9706572970185 bayes_pls_golite062009
  • protein binding
    		•  0.853351196918381 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.67392957114349 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.44172618015361 bayes_pls_golite062009
  • transcription factor binding
    		•  0.22865859991459 bayes_pls_golite062009
  • chromatin binding
    		•  0.203837749053719 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle