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Protein Overview: sfa-1

General Information:
Name(s) found: sfa-1 / CE28108 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00013808 locus:sfa-1 status:Confirmed UniProt:G5EF97 protein_id:CAB55136.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 699 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: nematode larval development [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed article]
    mRNA processing [IEALink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: nucleic acid binding [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    RNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKTGGNTEP MPFIRKWGNE AGEDLGAAPS ATAAPPPALV VPTISSMSSG DNKSPSRSES  60
   61 VSDRKRDRSR SRDRDRKKDR KKKDRSRERD RERRSSRSRS RSPRDRDRER RRRRSRSPPP 120
  121 RRRSRSGGDR RRRERSPPSM VPNSPQRVKE PVINPLIRED LAAAVESGAV PVEAVQAGAV 180
  181 VALNPAKKER RSRWSTTKSF VPGMPTILPA DLTEDQRNAY LLQLEIEDAT RKLRLADFGV 240
  241 AEGRERSPSP EPVYDANGKR LNTREVRKRQ ELEQLRHEKI QALLKINPNF KPPADYRAPN 300
  301 IRLHDKVWIP QEQFPDLNFV GLLIGPRGNT LKSLEAETGA KIIIRGKGSI KEGKLTNRLG 360
  361 PMPGENEPLH AYVTGTDMNV IKKACEKIKQ VIAEATALPD NNELRKLQLR ELALLNGTFR 420
  421 PEDLANGARC SNCGSDEHKS WECPDAPNVT NQIKCTNCGA FGHISKDCKN PKGMYASEAG 480
  481 MDDEYSALMA ELGETPAAGA GAGGGGGGHV ASAGGGISAM TGAGGEAPGG GAGGRGGGAH 540
  541 GGAGRGGGYQ GGRGGGRGFQ NPRDLFGPPK GEEEQQQQAN ASMQHGYYDH YQQYAYPNQY 600
  601 QQPYGAPAPP GGSAYGHQQQ QQQQQQQDYS DFYTSPGARG GAGAKANKGW YGSGGGSSMP 660
  661 MPVPPPGGLG GFMPPPPPPP PMPGDLSSLL AAAPPPPPS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..135] MSA 4.077995 View MSA. No confident structure predictions are available.
    2 View Details [136..259] deduced N/A No confident structure predictions are available.
    3 View Details [260..416] PSI-BLAST 32.39794 RNA splicing factor 1
    4 View Details [417..509] FFAS03 2.05 No description for 2ihxA was found.
    5 View Details [510..699] PSI-BLAST 5.0 No description for 1y0fB was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • nucleic acid binding
    		•  4.28581120742478 bayes_pls_golite062009
  • RNA binding
    		•  4.07234389285213 bayes_pls_golite062009
  • binding
    		•  3.45962790790935 bayes_pls_golite062009
  • mRNA binding
    		•  2.74771386314615 bayes_pls_golite062009
  • protein binding
    		•  2.21586499514642 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.01194399592256 bayes_pls_golite062009
  • DNA binding
    		•  1.78469836520678 bayes_pls_golite062009
  • transcription factor activity
    		•  0.866815968834173 bayes_pls_golite062009
    		• 0.649281624091344 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.64468203163713 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.594072241231183 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.28490151670131 bayes_pls_golite062009
  • transcription activator activity
    		•  0.210494225017032 bayes_pls_golite062009
  • transcription factor binding
    		•  0.139588254197875 bayes_pls_golite062009
  • catalytic activity
    		•  0.113112541746059 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle