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Protein Overview: csn-2

General Information:
Name(s) found: csn-2 / CE27562 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00000814 locus:csn-2 COP9 signalosome complex subunit 2 status:Confirmed UniProt:O01422 protein_id:CCD61197.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 495 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: embryonic cleavage [IMPLink to PubMed articleLink to PubMed article]
    establishment of mitotic spindle orientation [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    oviposition [IMPLink to PubMed article]
    cytokinesis [IMPLink to PubMed articleLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDEYMDDDE DYGFEYEDDS GSEPDVDMEN QYYTAKGLRS DGKLDEAIKS FEKVLELEGE  60
   61 KGEWGFKALK QMIKITFGQN RLEKMLEYYR QLLTYIKSAV TKNYSEKSIN AILDYISTSR 120
  121 QMDLLQHFYE TTLDALKDAK NERLWFKTNT KLGKLFFDLH EFTKLEKIVK QLKVSCKNEQ 180
  181 GEEDQRKGTQ LLEIYALEIQ MYTEQKNNKA LKWVYELATQ AIHTKSAIPH PLILGTIREC 240
  241 GGKMHLRDGR FLDAHTDFFE AFKNYDESGS PRRTTCLKYL VLANMLIKSD INPFDSQEAK 300
  301 PFKNEPEIVA MTQMVQAYQD NDIQAFEQIM AAHQDSIMAD PFIREHTEEL MNNIRTQVLL 360
  361 RLIRPYTNVR ISYLSQKLKV SQKEVIHLLV DAILDDGLEA KINEESGMIE MPKNKKKMMV 420
  421 TSLVVPNAGD QGTTKSDSKP GTSSEPSTTT SVTSSILQGP PATSSCHQEL SMDGLRVWAE 480
  481 RIDSIQSNIG TRIKF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..495] PSI-BLAST 18.0 The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity
    		•  2.78419126863783 bayes_pls_golite062009
  • binding
    		•  2.71974493738804 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.36571535004008 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.03244296439384 bayes_pls_golite062009
  • DNA binding
    		•  1.95874073664777 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  1.6361512508718 bayes_pls_golite062009
  • protein binding
    		•  1.6279032205159 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  1.51715099535911 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.41858884169884 bayes_pls_golite062009
  • transcription factor activity
    		•  1.21805666483342 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.956814399390664 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.562731406491727 bayes_pls_golite062009
  • transcription factor binding
    		•  0.518146612491969 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.30464889749774 bayes_pls_golite062009
  • transferase activity
    		•  0.127854220687373 bayes_pls_golite062009
  • transcription activator activity
    		•  0.0593768116971065 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle