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Protein Overview: CE27373

General Information:
Name(s) found: CE27373 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00017640 status:Partially_confirmed UniProt:Q19655 protein_id:CCD68327.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 549 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: electron transport [IEALink to PubMed article]
    glutamate biosynthetic process [IEALink to PubMed article]
    removal of superoxide radicals [IEALink to PubMed article]
    glutathione metabolic process [IEALink to PubMed article]
    detoxification of mercury ion [IEALink to PubMed article]
    Molecular Function: disulfide oxidoreductase activity [IEALink to PubMed article]
    NADP or NADPH binding [IEALink to PubMed article]
    oxidoreductase activity [IEALink to PubMed article]
    FAD binding [IEALink to PubMed article]
    oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [IEALink to PubMed article]
    NAD or NADH binding [IEALink to PubMed article]
    mercury ion binding [IEALink to PubMed article]
    mercury (II) reductase activity [IEALink to PubMed article]
    thioredoxin-disulfide reductase activity [IEALink to PubMed article]
    glutathione-disulfide reductase activity [IEALink to PubMed article]
    oxidoreductase activity, acting on NADH or NADPH [IEALink to PubMed article]
    dihydrolipoyl dehydrogenase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALANWLTPV EPECDNDDSP AVEEILGRIE DVPPGTKKMF EVRDRKVLVI NDEGRIYAIN  60
   61 GLCSHYNFSL ENGTYAKGRI RCPLHGACFN VRSGDIEDYP GFDSLHSYVV TVNDGNLIIK 120
  121 TTEKKLGSDR RIRHLPKMKQ CNDRPVVIIG GGVATATFIE HSRLNGLITP ILVISEESLP 180
  181 PYDRVLLSKK PAATGEDIRL RKDDAFYEER NVKFLLKTSV IAVNHKSREV SLSNGETVVY 240
  241 SKLIIATGGN VRKLQVPGSD LKNICYLRKV EEANIISNLH PGKHVVCVGS SFIGMEVASA 300
  301 LAEKAASVTV ISNTPEPLPV FGSDIGKGIR LKFEEKGVKF ELAANVVALR GNDQGEVSKV 360
  361 ILENGKELDV DLLVCGIGVT PATKFLEGSG IKLDNRGFIE VDEKFRTNIS YIFAMGDVVT 420
  421 APLPLWDIDS INIQHFQTAQ AHGQHLGYTI VGKPQPGPIV PYFWTLFFFA FGLKFSGCNQ 480
  481 GSTKEYTNGD PETGTFIRYF LKKDKVVAVA AGGPSSVASQ FAEIFKKGIE VTLKDLKNSS 540
  541 DHTWGHLLL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..138] PSI-BLAST 15.0 Crystal structure of the terminal oxygenase component of carbazole 1,9a-dioxygenase, a non-heme iron oxygenase system catalyzing the novel angular dioxygenation for carbazole and dioxin
    2 View Details [139..549] PSI-BLAST 60.69897 Crystal Structure of Putidaredoxin Reductase from Pseudomonas putida

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquinol-cytochrome-c reductase activity
    		•  6.1967513598129 bayes_pls_golite062009
  • oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
    		•  6.1967513598129 bayes_pls_golite062009
  • oxidoreductase activity, acting on diphenols and related substances as donors
    		•  5.66776915951861 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  3.88156638601211 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  3.73845396527802 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.19845820927381 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  3.1835578543172 bayes_pls_golite062009
  • electron carrier activity
    		•  2.99570246405422 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.89446748006871 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.6893938608151 bayes_pls_golite062009
  • oxidoreductase activity, acting on other nitrogenous compounds as donors
    		•  2.10394407031598 bayes_pls_golite062009
  • binding
    		•  1.72571699341388 bayes_pls_golite062009
  • protein binding
    		•  1.42812507064708 bayes_pls_golite062009
  • catalytic activity
    		•  0.746741393172769 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
    		•  0.40898590798487 bayes_pls_golite062009
    2
    Term Confidence Notes
  • oxidoreductase activity, acting on NADH or NADPH
    		•  6.31162710673112 bayes_pls_golite062009
  • oxidoreductase activity
    		•  4.83215507169904 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  4.48151296542899 bayes_pls_golite062009
  • antioxidant activity
    		•  3.99666840824738 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor
    		•  3.14220680303959 bayes_pls_golite062009
  • dihydrolipoyl dehydrogenase activity
    		•  2.64996407196586 bayes_pls_golite062009
  • NADH dehydrogenase activity
    		•  2.52849995398093 bayes_pls_golite062009
  • catalytic activity
    		•  2.35839632763616 bayes_pls_golite062009
  • disulfide oxidoreductase activity
    		•  1.87417564758524 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  1.51669656835992 bayes_pls_golite062009
  • binding
    		•  1.50672625307126 bayes_pls_golite062009
  • oxygen-dependent protoporphyrinogen oxidase activity
    		•  1.40095976457767 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  1.38559418221892 bayes_pls_golite062009
  • protein binding
    		•  1.21627488765992 bayes_pls_golite062009
  • glutathione disulfide oxidoreductase activity
    		•  1.03742390358385 bayes_pls_golite062009
  • peptide disulfide oxidoreductase activity
    		•  1.03742390358385 bayes_pls_golite062009
  • glutathione-disulfide reductase activity
    		•  0.99066334151721 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.89753364903289 bayes_pls_golite062009
  • thioredoxin-disulfide reductase activity
    		•  0.726677331033932 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.694937108363567 bayes_pls_golite062009
  • NADPH-adrenodoxin reductase activity
    		•  0.684108511779641 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.535357395213029 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors
    		•  0.36771673037999 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.78

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle