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Protein Overview: frs-3

General Information:
Name(s) found: frs-3 / CE26224 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00013361 locus:fars-2 status:Confirmed UniProt:G5ECI8 protein_id:CAB60398.3 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 458 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: tRNA aminoacylation for protein translation [IEALink to PubMed article]
    phenylalanyl-tRNA aminoacylation [IEALink to PubMed article]
    translation [IEALink to PubMed article]
    Molecular Function: nucleotide binding [IEALink to PubMed article]
    ATP binding [IEALink to PubMed article]
    aminoacyl-tRNA ligase activity [IEALink to PubMed article]
    phenylalanine-tRNA ligase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRFLSTYQTG ARRCCTMLFQ KNAKSIRATL MSTTAAAEES RKIVKEEVFE LDGRKYTPDA  60
   61 LYNLSPGVRR LLDRRILQES SNPLNLLKRR IVDYVHQTYR KPGNRSPLFT ICESEPRVVT 120
  121 TYQNFDSLLT PEDHVSRRPS DTYYVNHEHC LRAHTSAHQH NLMQSGLDAF LVIGDVYRRD 180
  181 EVDRTHYPCF HQIEGVRLYS KDELLGKKPD GKNVAELFST AASAATERSP EKQEKHTLDA 240
  241 TKAAEIQLKQ FLENLCDELF GKDAEKRWVD AYFPFTHPSW ELEVFYNGQW LEVLGCGIME 300
  301 QKLLESAGVT DKIGWAFGIG LERIAMVLYG IPDIRLFWSK DTGFLSQFAG KMPGEDVKYK 360
  361 QISAHPQVIF DISFFLPSTV QFNDMTSDVY DTIRTVGGEL VEQVKLTDEF ENKKKEKKSQ 420
  421 TYRIVYRSHE RALTKEEVNV IHKQIEQSLA SSFGVTLR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..349] PSI-BLAST 62.69897 Phenyl-tRNA synthetase (PheRS) alpha subunit, PheS
    2 View Details [350..458] PSI-BLAST 23.09691 No description for 2du7A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.89468709683036 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  7.89468709683036 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.88410036819636 bayes_pls_golite062009
  • phenylalanine-tRNA ligase activity
    		•  7.1807508219467 bayes_pls_golite062009
  • ligase activity
    		•  6.92073480193262 bayes_pls_golite062009
  • serine-tRNA ligase activity
    		•  2.46505535069103 bayes_pls_golite062009
  • glycine-tRNA ligase activity
    		•  2.29229136935761 bayes_pls_golite062009
  • threonine-tRNA ligase activity
    		•  2.18642354927 bayes_pls_golite062009
  • catalytic activity
    		•  1.99372273395202 bayes_pls_golite062009
  • alanine-tRNA ligase activity
    		•  1.82594054955281 bayes_pls_golite062009
  • lysine-tRNA ligase activity
    		•  1.72324031407565 bayes_pls_golite062009
  • histidine-tRNA ligase activity
    		•  1.72215103383322 bayes_pls_golite062009
  • binding
    		•  0.966824335333342 bayes_pls_golite062009
  • asparagine-tRNA ligase activity
    		•  0.921492123574877 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.375542987753806 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.281662799812287 bayes_pls_golite062009
  • protein binding
    		•  0.0804954454681041 bayes_pls_golite062009
  • DNA binding
    		•  0.0309732052586011 bayes_pls_golite062009
  • RNA binding
    		•  0.0221706730298825 bayes_pls_golite062009
  • aspartate-tRNA ligase activity
    		•  0.00572514744734753 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle