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View Structure Prediction Details

Protein: frs-3
Organism: Caenorhabditis elegans
Length: 458 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for frs-3.

Description E-value Query
Range
Subject
Range
gi|49457552, gi|... - gi|49457552|emb|CAG47075.1| FARS1 [Homo sapiens], gi|189065522|dbj|BAG35361.1| unnamed protein produ...
357.0 [0..28] [458..30]

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Predicted Domain #1
Region A:
Residues: [1-349]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRFLSTYQTG ARRCCTMLFQ KNAKSIRATL MSTTAAAEES RKIVKEEVFE LDGRKYTPDA  60
   61 LYNLSPGVRR LLDRRILQES SNPLNLLKRR IVDYVHQTYR KPGNRSPLFT ICESEPRVVT 120
  121 TYQNFDSLLT PEDHVSRRPS DTYYVNHEHC LRAHTSAHQH NLMQSGLDAF LVIGDVYRRD 180
  181 EVDRTHYPCF HQIEGVRLYS KDELLGKKPD GKNVAELFST AASAATERSP EKQEKHTLDA 240
  241 TKAAEIQLKQ FLENLCDELF GKDAEKRWVD AYFPFTHPSW ELEVFYNGQW LEVLGCGIME 300
  301 QKLLESAGVT DKIGWAFGIG LERIAMVLYG IPDIRLFWSK DTGFLSQFA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 62.69897
Match: 1b70A
Description: Phenyl-tRNA synthetase (PheRS) alpha subunit, PheS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming aminoacyl-tRNA and related compounds 7.89468709683036 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 7.89468709683036 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 7.88410036819636 bayes_pls_golite062009
phenylalanine-tRNA ligase activity 7.1807508219467 bayes_pls_golite062009
ligase activity 6.92073480193262 bayes_pls_golite062009
serine-tRNA ligase activity 2.46505535069103 bayes_pls_golite062009
glycine-tRNA ligase activity 2.29229136935761 bayes_pls_golite062009
threonine-tRNA ligase activity 2.18642354927 bayes_pls_golite062009
catalytic activity 1.99372273395202 bayes_pls_golite062009
alanine-tRNA ligase activity 1.82594054955281 bayes_pls_golite062009
lysine-tRNA ligase activity 1.72324031407565 bayes_pls_golite062009
histidine-tRNA ligase activity 1.72215103383322 bayes_pls_golite062009
binding 0.966824335333342 bayes_pls_golite062009
asparagine-tRNA ligase activity 0.921492123574877 bayes_pls_golite062009
transcription regulator activity 0.375542987753806 bayes_pls_golite062009
nucleic acid binding 0.281662799812287 bayes_pls_golite062009
protein binding 0.0804954454681041 bayes_pls_golite062009
DNA binding 0.0309732052586011 bayes_pls_golite062009
RNA binding 0.0221706730298825 bayes_pls_golite062009
aspartate-tRNA ligase activity 0.00572514744734753 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [350-458]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKMPGEDVKY KQISAHPQVI FDISFFLPST VQFNDMTSDV YDTIRTVGGE LVEQVKLTDE  60
   61 FENKKKEKKS QTYRIVYRSH ERALTKEEVN VIHKQIEQSL ASSFGVTLR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.09691
Match: 2du7A
Description: No description for 2du7A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle