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Protein Overview: CE25610

General Information:
Name(s) found: CE25610 [WormBase]
Description(s) found:
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  • WBGene00022306 status:Confirmed UniProt:Q9N4A5 protein_id:CCD72586.1 [WormBase]
  • gi|7105688|gb|AAF36071.1| Hypothetical protein Y77E11A.1 [Caenorhabditis elegans] [NCBI NR]
  • gi|17544236|ref|NP_500088.1| hypothetical protein Y77E11A.1 [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE25610 WBGene00022306 status:Partially_confirmed TR:Q9N4A5 protein_id:AAF36071.1 [wormpep150.fasta]
  • 25610 WBGene00022306 status:Partially_confirmed TR:Q9N4A5 protein_id:AAF36071.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • hexokinase (50.1 kD) (4C273) [Caenorhabditis elegans]gi|7105688|gb|AAF36071.1| Hypothetical protein Y77E11A.1 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • status:Partially_confirmed TR:Q9N4A5 protein_id:AAF36071.1 [wormpep115.fasta.reversed]
  • CE25610 status:Partially_confirmed TR:Q9N4A5 protein_id:AAF36071.1 [wormpep80.hongbin]
  • CE25610 WBGene00022306 status:Confirmed UniProt:Q9N4A5_CAEEL protein_id:AAF36071.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE25610 WBGene00022306 status:Confirmed UniProt:Q9N4A5_CAEEL protein_id:AAF36071.1| [wormORF-contam.fasta]
  • Hypothetical protein Y77E11A.1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Y77E11A.1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE25610 WBGene00022306 status:Confirmed TR:Q9N4A5 protein_id:AAF36071.1 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE25610 WBGene00022306 status:Confirmed UniProt:Q9N4A5 protein_id:AAF36071.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • CE25610 WBGene00022306 status:Confirmed UniProt:Q9N4A5 protein_id:CCD72586.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE25610 WBGene00022306 locus:hxk-3 status:Confirmed UniProt:Q9N4A5 protein_id:CCD72586.1 Hexokinase [c_elegans-PRJNA13758-WS250-ecoli-contam.fasta]
  • Hexokinase OS=Caenorhabditis elegans GN=hxk-3 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 451 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: glycolysis [IEALink to PubMed article]
    Molecular Function: ATP binding [IEALink to PubMed article]
    hexokinase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVLPPEVEE ILAKFRLNRE QLQEISEKVE QQMKMGLAKT QGSSIAMLPS YVPALPDGTE  60
   61 TGKYVAIDLS GKNLRIMLLT MNGAGTTPTH ETVNYIVANH VMKGTGDQLF TFIVNCLQRF 120
  121 LQEFGLVDAN LPIGFVFSYP CELLSIRSAR LLWWTKGFDI KDCLQRDIVA LLEEALEMNM 180
  181 STKVSIKAVM NDTVGQLAAA AHKYGPECTI GVVIGYGCNS SYLEKTSRIT KFDAKARGYD 240
  241 HDNMIVVTEW EEFGKHGELD DILTQFDREV DAASVHKGKQ LIDKLCGALY IGEVVRRVLS 300
  301 QLVLDRVLFE GQSCEKLDED ESFPTKYISE ILGEEEGVFK ACRRICEELE VEMHGTGDYI 360
  361 IIREVCDVIS RRGASIVAAA ISALLRHLEL SSVKIGVGGA LIQFHPTYHQ MLKEKLEELT 420
  421 PITMKFELVP ADEGSCQGAA LIAAVAERLK L

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..451] PSI-BLAST 161.0 Mammalian type I hexokinase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • kinase activity
    		•  2.81480196738665 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  2.66634930184926 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.47806699612578 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  2.33338276303563 bayes_pls_golite062009
  • binding
    		•  2.11855816699924 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.09111975841662 bayes_pls_golite062009
  • protein binding
    		•  2.00711904074672 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.84294882554466 bayes_pls_golite062009
  • hexokinase activity
    		•  1.70516840340504 bayes_pls_golite062009
  • DNA binding
    		•  1.70014394990425 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.69431775343358 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  1.58791290104307 bayes_pls_golite062009
  • glucose binding
    		•  1.58717365638543 bayes_pls_golite062009
  • transferase activity
    		•  1.58048472128722 bayes_pls_golite062009
  • transcription activator activity
    		•  1.35676801272576 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.30214785132007 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.30181101672725 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.27871475799533 bayes_pls_golite062009
  • myosin binding
    		•  1.26046360733002 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  1.18894708772738 bayes_pls_golite062009
  • transcription factor activity
    		•  1.06678984888387 bayes_pls_golite062009
  • structural molecule activity
    		•  0.998075030492697 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.908385694796738 bayes_pls_golite062009
  • mannokinase activity
    		•  0.766256764215041 bayes_pls_golite062009
  • actin binding
    		•  0.742062735414161 bayes_pls_golite062009
  • protein kinase activity
    		•  0.659672620542945 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.574998559133169 bayes_pls_golite062009
  • hydrolase activity
    		•  0.474893704700898 bayes_pls_golite062009
  • glucokinase activity
    		•  0.47468456642723 bayes_pls_golite062009
  • sugar binding
    		•  0.44352406324938 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.426216374317549 bayes_pls_golite062009
  • ATP binding
    		•  0.39408967688855 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.358452809509562 bayes_pls_golite062009
  • ATPase activity
    		•  0.338933039062396 bayes_pls_golite062009
  • catalytic activity
    		•  0.296484721581333 bayes_pls_golite062009
  • monosaccharide binding
    		•  0.20435276425198 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.173637392484485 bayes_pls_golite062009
  • nucleotide binding
    		•  0.168207023557983 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.104339549630743 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.101742118226005 bayes_pls_golite062009
  • chromatin binding
    		•  0.0489277194984092 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle