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Protein Overview: csn-4

General Information:
Name(s) found: csn-4 / CE25482 [WormBase]
Description(s) found:
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  • WBGene00000816 locus:csn-4 COP9 signalosome complex subunit 4 status:Confirmed UniProt:Q9N359 protein_id:CCD74073.1 [WormBase]
  • gi|7332116|gb|AAF60803.1| Cop-9 signalosome subunit protein 4 [Caenorhabditis elegans] [NCBI NR]
  • gi|55976608|sp|Q9N359.1|CSN4_CAEEL RecName: Full=COP9 signalosome complex subunit 4; Short=Signalosome subunit 4 [NCBI NR]
  • gi|17543668|ref|NP_500034.1| COP-9 SigNalosome subunit family member (csn-4) [Caenorhabditis elegans] [NCBI NR]
  • COP9 signalosome complex subunit 4 OS=Caenorhabditis elegans GN=csn-4 PE=1 SV=1 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE25482 WBGene00000816 locus:csn-4 status:Confirmed SW:Q9N359 protein_id:AAF60803.1 [wormpep150.fasta]
  • 25482 WBGene00000816 locus:csn-4 status:Confirmed TR:Q9N359 protein_id:AAF60803.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • constitutive photomorphogenic COP9 SigNalosome subunit (46.1 kD) (csn-4) [Caenorhabditis elegans]gi|7332116|gb|AAF60803.1| Cop-9 signalosome subunit protein 4 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE25482 WBGene00000816 locus:csn-4 status:Confirmed TR:Q9N359 protein_id:AAF60803.1 [wormpep132.fasta]
  • 25482 WBGene00000816 locus:csn-4 status:Confirmed SW:Q9N359 protein_id:AAF60803.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • locus:csn-4 status:Confirmed TR:Q9N359 protein_id:AAF60803.1 [wormpep115.fasta.reversed]
  • CE25482 status:Partially_confirmed TR:Q9N359 protein_id:AAF60803.1 [wormpep80.hongbin]
  • CE25482 WBGene00000816 locus:csn-4 status:Confirmed UniProt:Q9N359 protein_id:AAF60803.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE25482 WBGene00000816 locus:csn-4 status:Confirmed UniProt:Q9N359 protein_id:AAF60803.1| [wormORF-contam.fasta]
  • COP9 signalosome complex subunit 4 (Signalosome subunit 4) [nr-271106-contam.fasta]
  • COP-9 SigNalosome subunit family member (csn-4) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Cop-9 signalosome subunit protein 4 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE25482 WBGene00000816 locus:csn-4 status:Confirmed UniProt:Q9N359 protein_id:CCD74073.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE25482 WBGene00000816 locus:csn-4 status:Confirmed UniProt:Q9N359 protein_id:CCD74073.1 COP9 signalosome complex subunit 4 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 412 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: embryonic cleavage [IMPLink to PubMed article]
    establishment of mitotic spindle orientation [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    cytokinesis [IMPLink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGEIERSQE VAVIFAQDTD HKAQYEALAK LCNKYLPQNA MGRVDTAEII KIIDTVIALE  60
   61 TGSMVVSRQF VSLITERLDN QHLESECVKA ISEGILAIIK TRTISYEDQV CILRLMLASL 120
  121 YEKEGRIKDA AQALIAINSD TSPKFNGPQA AKEGAKAQLC IRITKLLLDC SEIDEAEQYV 180
  181 NRTSILMVDL GANPDIQIEH KALQARVSDA KRRFVEAAQR YYELSATEQL PNSDKLTALG 240
  241 KAIVCVLLAK PGPQRSRLLT LIFKDERAPK CASFELIAKM YLTKVIHKDE LEEFEHQLQD 300
  301 HQKADEHGES ILKGVIQEHN ITAISQLYIN ISFKTLGQLL GVDTEAAESM AGEMISSERL 360
  361 HGYIDQTNGI LHFEDSNPMR VWDSQILSTL EQINKVSDMI VARHSEFAEF LT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..138] MSA 3.348995 View MSA. No confident structure predictions are available.
    2 View Details [139..300] MSA 2.399996 View MSA. No confident structure predictions are available.
    3 View Details [301..412] PSI-BLAST 10.69897 Solution structure of the PCI domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • transcription regulator activity
    		•  5.09178084244715 bayes_pls_golite062009
  • DNA binding
    		•  4.69269372393889 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.59221092058767 bayes_pls_golite062009
  • transcription factor activity
    		•  4.01234546864709 bayes_pls_golite062009
  • binding
    		•  3.52874320222492 bayes_pls_golite062009
  • transcription repressor activity
    		•  3.28015281691988 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.23304004014963 bayes_pls_golite062009
  • transcription activator activity
    		•  2.21230033124772 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.40206639526766 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  1.27763700765562 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  1.12147035668008 bayes_pls_golite062009
  • transcription factor binding
    		•  0.78051974537344 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.754042916649094 bayes_pls_golite062009
  • protein binding
    		•  0.753698599635855 bayes_pls_golite062009
  • specific transcriptional repressor activity
    		•  0.59003343009795 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.486434906547244 bayes_pls_golite062009
  • hydrolase activity
    		•  0.140191206949582 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle