Protein Overview: vrs-2

General Information:
Name(s) found:	vrs-2 / CE24685 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00006936 locus:vars-2 Valine--tRNA ligase status:Confirmed UniProt:Q9U1Q4 protein_id:CAB60428.1 [WormBase] gi\|75025236\|sp\|Q9U1Q4.1\|SYV_CAEEL RecName: Full=Valyl-tRNA synthetase; AltName: Full=Valine--tRNA ligase; Short=ValRS [NCBI NR] gi\|6425518\|emb\|CAB60428.1\| C. elegans protein Y87G2A.5, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|17510661\|ref\|NP_493377.1\| Valyl tRNA Synthetase family member (vrs-2) [Caenorhabditis elegans] [NCBI NR] Valine--tRNA ligase OS=Caenorhabditis elegans GN=vrs-2 PE=1 SV=1 [Swiss-Prot] [wormpep67.fasta] CE24685 WBGene00006936 locus:vrs-2 status:Partially_confirmed TR:Q9U1Q4 protein_id:CAB60428.1 [wormpep150.fasta] 24685 WBGene00006936 locus:vrs-2 status:Partially_confirmed TR:Q9U1Q4 protein_id:CAB60428.1 [wormpep130-phg-ecoli-orf-rand.fasta] valyl tRNA Synthetase (118.9 kD) (vrs-2) [Caenorhabditis elegans]gi\|6425518\|emb\|CAB60428.1\| Hypothetical protein Y87G2A.5 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas] locus:vrs-2 status:Partially_confirmed TR:Q9U1Q4 protein_id:CAB60428.1 [wormpep115.fasta.reversed] CE24685 locus:vrs-2 status:Partially_confirmed TR:Q9U1Q4 protein_id:CAB60428.1 [wormpep80.hongbin] CE24685 WBGene00006936 locus:vrs-2 status:Confirmed UniProt:SYV_CAEEL protein_id:CAB60428.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE24685 WBGene00006936 locus:vrs-2 status:Confirmed UniProt:SYV_CAEEL protein_id:CAB60428.1\| [wormORF-contam.fasta] Hypothetical protein Y87G2A.5 [Caenorhabditis elegans] [nr-271106-contam.fasta] Valyl tRNA Synthetase family member (vrs-2) [Caenorhabditis elegans] [nr-271106-contam.fasta] Valyl-tRNA synthetase (Valine--tRNA ligase) (ValRS) [nr-271106-contam.fasta] CE24685 WBGene00006936 locus:vrs-2 status:Confirmed SW:Q9U1Q4 protein_id:CAB60428.1 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE24685 WBGene00006936 locus:vrs-2 status:Confirmed UniProt:Q9U1Q4 protein_id:CAB60428.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] CE24685 WBGene00006936 locus:vars-2 status:Confirmed UniProt:Q9U1Q4 protein_id:CAB60428.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] CE24685 WBGene00006936 locus:vars-2 status:Confirmed UniProt:Q9U1Q4 protein_id:CAB60428.1 Valine--tRNA ligase [wormpep246-ecoli-contam.fasta]
Organism:	Caenorhabditis elegans
Length:	1050 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IEA]
Biological Process:	isoleucyl-tRNA aminoacylation [IEA] tRNA aminoacylation for protein translation [IEA] leucyl-tRNA aminoacylation [IEA] valyl-tRNA aminoacylation [IEA] nematode larval development [IMP] embryonic development ending in birth or egg hatching [IMP ] positive regulation of growth rate [IMP] methionyl-tRNA aminoacylation [IEA] reproduction [IMP ] growth [IMP] positive regulation of multicellular organism growth [IMP] translation [IEA]
Molecular Function:	nucleotide binding [IEA] valine-tRNA ligase activity [IEA] ATP binding [IEA] aminoacyl-tRNA ligase activity [IEA] leucine-tRNA ligase activity [IEA] isoleucine-tRNA ligase activity [IEA] methionine-tRNA ligase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDPAGNRPK TEKELKKEAE KAAKLAKFEE KQKKLAEKKA AASDKPVKEA KAKKEQTVEA  60
   61 AEPVDQTPTG QRKKIDGEIP AAYFPGYVES GWYSWWEKEG FFKPEYIDKL NPGSNPADSF 120
  121 TVCIPPPNVT GNLHVGHALA TTVEDTITRF NRMHGKRTLF NPGCDHAGIA TQVVVEKRLK 180
  181 RERGLTRHDL GRDRFNQEVW HWKNEKGDVI YDQFRKLGAS VDWDRAVFTM DPKMCRAVTE 240
  241 AFIRMHESGT IYRSNRLVNW SCALRSAISD IEVDKKELTG STLIAVPGYD KKIEFGVLNS 300
  301 FAYKIQGSDE EIVVSTTRIE TMLGDSGVAV HPDDQRYKHL VGKQCIHPFI PTRNLPIFAD 360
  361 SFVEMEFGTG AVKITPAHDH NDYEVGIRQN LPFHNCITDD GLISQGCGEF SGMKRFDART 420
  421 AVIEALKEKG LYRGKEDNPM VVPTCSRSKD VIEPILKPQW YVKCAHMAEK AVAAVANGDL 480
  481 QIIPEFHKAT WNRWLESSRD WCISRQLWWG HRIPAYYISF ADGREQPLPE ENYWVSARTE 540
  541 QEALAKAAQK FQVPEAEILL KWDEDVLDTW FSSGMWPFAV FGWPDATKDM DLFFPGAVLE 600
  601 TGHDILFFWV ARMVFMAQEL TGKLPFKEIL LHAMIRDAHG RKMSKSLGNV IDPLDVIRGI 660
  661 SLNDLQAQLL GGNLDEKEIA VAKEGQARDY PDGIPECGVD ALRFALLSYT SQGRDINLDV 720
  721 LRVHGYRKFC NKLWQVVRFA LARISDKPEQ KPTFEINLKS ATPTDLWILS RLAKAVKETN 780
  781 EALKAYNFTQ ATTVTYNFWL YDFCDVYVET IKPVLYGDNT TLRQVAISVL HKCIDTGLRL 840
  841 ISPLMPFISE ELWQRMPRLD DSDYTSPSII VAQYPLTQKY EKYQNEKLEA AFEFAQELIG 900
  901 KVRSLRADYD LKKTKITMQI LSETPEDESM LNDISAVITT LTFSEKVSIL NKCESDKIEK 960
  961 GSAHIACGGR CQVYINLTGI IDVPKEIEKL GAKLQKNQIS VKKIGDIQSS ADYEQKVPVD1020
 1021 IRALDQEKKA TLEKEIENIT AAIAQLKALN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	hcp-1	hcp1 IP from december2004	Cheeseman, I.M., et al. (2005)
View Run	hcp-2	hcp2 ip from december	Cheeseman, I.M., et al. (2005)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: vrs-2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: