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Protein Overview: nhr-237

General Information:
Name(s) found: nhr-237 / CE24323 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00021610 locus:nhr-237 status:Partially_confirmed UniProt:Q966B8 protein_id:CCD69586.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 345 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: response to antibiotic [IEALink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    beta-lactam antibiotic catabolic process [IEALink to PubMed article]
    Molecular Function: transcription factor activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    steroid hormone receptor activity [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]
    beta-lactamase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEIPTPHQIC RVCGECADAV HFGALSCRAC AAFFRRKVAA GKPLSSSRCS GSCKLENQVL  60
   61 RRLCAKCRYE KCVQVGMRTS AVLSRLAVKS EPEFESLLDQ IKLAYERLQM ARKEAFHTEG 120
  121 HIPKMIKYQE MHKMCSFDLQ LVSQHFTSIF QSLTPISEAQ KVTLGEYFTV PFVLLDGSYR 180
  181 SVESDYIVFP NGDYVDAQNI DAFYQNPDEK DESIGSSVAS ILEPYWRLHH QTLWEQMKKV 240
  241 KPSLIEFLVL SAFIFWDFGL QGQSEECIKV CNQLRARVNA ELSTYEKTFY TAGDYSLRVA 300
  301 EVVYLLQSVQ KSLAIMHSCK TLGYVFDFRD RTCPLNDNLE KTHSK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..73] PSI-BLAST 15.69897 No description for 2hanB was found.
    2 View Details [74..345] PSI-BLAST 42.69897 LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.18770607371139 bayes_pls_golite062009
  • protein binding
    		•  0.699012253331291 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  2.07679393058916 bayes_pls_golite062009
  • protein binding
    		•  1.4692467191721 bayes_pls_golite062009
  • ligand-dependent nuclear receptor activity
    		•  1.46824905227088 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.44313615088064 bayes_pls_golite062009
  • receptor activity
    		•  1.27827487658808 bayes_pls_golite062009
  • DNA binding
    		•  1.07558579137079 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.885522697705667 bayes_pls_golite062009
  • signal transducer activity
    		•  0.875578759851886 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.875578759851886 bayes_pls_golite062009
  • transcription factor activity
    		•  0.58279231726985 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.25945001118854 bayes_pls_golite062009
  • transcription activator activity
    		•  0.15629984940944 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle