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Catalysis of the reaction: a cephalosporin + H2O = a substituted beta-amino acid derivative of the cephalosporin. Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds. Catalysis of the reaction: a penicillin + H2O = a substituted beta-amino acid derivative of the penicillin. Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amide. Catalysis of the reaction: a beta-lactam + H2O = a substituted beta-amino acid.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: beta-lactamase activity
Acc: GO:0008800
Aspect: Molecular Function
Desc: Catalysis of the reaction: a beta-lactam + H2O = a substituted beta-amino acid.
Synonyms:
  • beta-lactamase I-III
  • beta-lactamase AME I
  • exopenicillinase activity
  • cephalosporin-beta-lactamase activity
  • penicillin amido-beta-lactamhydrolase activity
  • neutrapen
  • penicillin beta-lactamase activity
  • penicillinase I, II
  • ampicillinase activity
  • beta-lactamase A, B, C
  • beta-lactam hydrolase activity
Proteins in PDR annotated with:
   This term: 37 [Search]
   Term or descendants: 37 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008800 - beta-lactamase activity (interactive image map)

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