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Protein Overview: ahr-1

General Information:
Name(s) found: ahr-1 / CE20561 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00000096 locus:ahr-1 Aryl hydrocarbon receptor protein 1 status:Confirmed UniProt:O44712 protein_id:CAB51463.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 602 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    intracellular [TASLink to PubMed article]
    Biological Process: signal transduction [IEALink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    response to xenobiotic stimulus [IDALink to PubMed article]
    regulation of transcription [IEALink to PubMed article][ISSLink to PubMed article]
    intracellular receptor mediated signaling pathway [TASLink to PubMed article]
    Molecular Function: DNA binding [IDALink to PubMed article]
    transcription regulator activity [IEALink to PubMed article][TASLink to PubMed article]
    signal transducer activity [IEALink to PubMed article][ISSLink to PubMed article]
    aryl hydrocarbon receptor activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYASKRRQRN FKRVRDPPKQ LTNTNPSKRH RERLNGELET VAMLLPYDSS TISRLDKLSV  60
   61 LRLAVSFLQC KAHFQACLHN SQFLSAGFPM STHSYSYQPH PPIPFSNKVP TIFDLRIGTP 120
  121 MLDPEESNFE EISLKSLGGF ILVLNDNGEI YYASENVENY LGFHQSDVLH QPVYDLIHSE 180
  181 DRDDIRQQLD SNFHIPTSSA SNQFDVFAPQ NSKYLERNVN ARFRCLLDNT CGFLRIDMRG 240
  241 KLMSLHGLPS SYVMGRTASG PVLGMICVCT PFVPPSTSDL ASEDMILKTK HQLDGALVSM 300
  301 DQKVYEMLEI DETDLPMPLY NLVHVEDAVC MAEAHKEAIK NGSSGLLVYR LVSTKTRRTY 360
  361 FVQSSCRMFY KNSKPESIGL THRLLNEVEG TMLLEKRSTL KAKLLSFDDS FLQSPRNLQS 420
  421 TAALPLPSVL KDDQDCLEPS TSNSLFPSVP VPTPTTTKAN RRRKENSHEI VPTIPSIPIP 480
  481 THFDMQMFDP SWNHGVHPPA WPHDVYHLTQ YPPTYPHPPG TVGYPDVQIA PVDYPGWHPN 540
  541 DIHMTQLPHG FTPDAQKLVP PHPQMSHFTE YPTPSTHHDL HHHPLKQDNF HLISEVTNLL 600
  601 GT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..109] PSI-BLAST 8.39794 SREBP-1a
    2 View Details [110..515] PSI-BLAST 50.69897 Crystal Structure of the PAS repeat region of the Drosophila clock protein PERIOD
    3 View Details [516..602] MSA 3.248997 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  3.17840258752324 bayes_pls_golite062009
  • DNA binding
    		•  2.56280954568684 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.54719844409677 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.42823673922558 bayes_pls_golite062009
  • transcription factor activity
    		•  2.29471798726915 bayes_pls_golite062009
  • protein binding
    		•  1.59929864805879 bayes_pls_golite062009
  • transcription factor binding
    		•  0.78456571881611 bayes_pls_golite062009
  • transcription activator activity
    		•  0.537618291807254 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.39197881175959 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.3402368922433 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle