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Protein Overview: unc-73

General Information:
Name(s) found: unc-73 / CE19467 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00006805 locus:unc-73 status:Confirmed UniProt:Q7JNG4 protein_id:CCD63879.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 552 amino acids

    Gene Ontology:
    Cellular Component: axon [IDALink to PubMed article]
    intracellular [IEALink to PubMed article]
    proteinaceous extracellular matrix [IEALink to PubMed article]
    Biological Process: Rac protein signal transduction [ICLink to PubMed article]
    male genitalia morphogenesis [IMP]
    regulation of Rho protein signal transduction [IEALink to PubMed article]
    DNA repair [IEALink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed article]
    regulation of locomotion [IMPLink to PubMed article]
    mesodermal cell migration [TASLink to PubMed article]
    locomotion [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article][NASLink to PubMed article]
    positive regulation of axon extension [IMPLink to PubMed article]
    cell adhesion [IEALink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    engulfment of apoptotic cell [IGILink to PubMed article]
    blood coagulation [IEALink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed article]
    regulation of vulval development [TASLink to PubMed article]
    positive regulation of locomotion [IMPLink to PubMed article]
    neuron migration [TASLink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    nematode larval development [NASLink to PubMed article]
    positive regulation of actin filament polymerization [IDALink to PubMed article]
    oviposition [IMPLink to PubMed articleLink to PubMed article][TASLink to PubMed article]
    cell migration [TASLink to PubMed article]
    Molecular Function: guanyl-nucleotide exchange factor activity [IEALink to PubMed article]
    Rho guanyl-nucleotide exchange factor activity [IEALink to PubMed article]
    Rac guanyl-nucleotide exchange factor activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPCANLMPRC KQEFRRIFAN SSKERAAAAN SSSSNNNSPA TRQSTSTSSP VTANGHTTES  60
   61 STSAPIGVLS SGEPTSSNSI PSSSTPTHTV PSSVPATVIP IVVAEDEKAE DCLPPPMENI 120
  121 TINNSIDEKD MNEDSVAASD AVEPEVALPA KVEKTPEETA RFKRSYVLME LVETEQDYVK 180
  181 DLTSVVEGYI GNLNKMDLPA DLVGKDKIIF ANIVNILEFH KTNFLKEIEK CSENYEAAGA 240
  241 AFVKYERRLH TLYVTYCQNK PKSDYLLAQD DFEAFFADTK AKLGHKVALC DLLIKPVQRI 300
  301 MKYQLLLKDI LKFTERAKDK TDTLKKALQV MHVVPKACDD MMQVGRLQNF DKSLSAQGKL 360
  361 IHQGTLQISE SIAGNVQKPK DRRIFLFEQS AIIADHIPPK KEFGNPTYIF KSQFMVNKMV 420
  421 FEPNVPDDPL RFVIKSSDPT QPTSFIANAQ SQEEKDEWNR KMSELLDQQK RLLAALVDPR 480
  481 RYNDMSSGMG DLSLGAPGGD RRGAPSSANR SAASSSKKPA ESPKKEGKSK SSLFSFGKKP 540
  541 AKSPTSPPPV GK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..154] MSA 1.494996 View MSA. No confident structure predictions are available.
    2 View Details [155..552] PSI-BLAST 65.221849 Dbl's big sister, Dbs


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle