Protein Overview: unc-73

General Information:
Name(s) found:	unc-73 / CE19466 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00006805 locus:unc-73 status:Confirmed UniProt:Q7JNG6 protein_id:CCD63878.1 [WormBase] gi\|71987150\|ref\|NP_001021498.1\| UNCoordinated family member (unc-73) [Caenorhabditis elegans] [NCBI NR] gi\|3844604\|gb\|AAC71110.1\| Uncoordinated protein 73, isoform c, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] pir\|\|A87749 protein F55C7.7c [imported] - Caenorhabditis elegans [NCBI NR] [wormpep67.fasta] CE19466 WBGene00006805 locus:unc-73 status:Confirmed TR:Q7JNG6 protein_id:AAC71110.1 [wormpep150.fasta] 19466 WBGene00006805 locus:unc-73 status:Partially_confirmed TR:Q7JNG6 protein_id:AAC71110.1 [wormpep130-phg-ecoli-orf-rand.fasta] Uncoordinated protein 73, isoform c [Caenorhabditis elegans]gi\|25395249\|pir\|\|A87749 protein F55C7.7c [imported] - Caenorhabditis elegans [nrdb_11152004_Chlamydomonas] CE19466 WBGene00006805 locus:unc-73 status:Partially_confirmed TR:Q7JNG6 protein_id:AAC71110.1 [wormpep132.fasta] 19466 WBGene00006805 locus:unc-73 status:Confirmed TR:Q7JNG6 protein_id:AAC71110.1 [wormpep150-phg-orf-ecoli-rand.fasta] locus:unc-73 status:Partially_confirmed TR:O61528 protein_id:AAC71110.1 [wormpep115.fasta.reversed] CE19466 status:Partially_confirmed [wormpep80.hongbin] CE19466 WBGene00006805 locus:unc-73 status:Confirmed UniProt:Q7JNG6_CAEEL protein_id:AAC71110.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE19466 WBGene00006805 locus:unc-73 status:Confirmed UniProt:Q7JNG6_CAEEL protein_id:AAC71110.1\| [wormORF-contam.fasta] Uncoordinated protein 73, isoform c [Caenorhabditis elegans] [nr-271106-contam.fasta] UNCoordinated family member (unc-73) [Caenorhabditis elegans] [nr-271106-contam.fasta] CE19466 WBGene00006805 locus:unc-73 status:Confirmed UniProt:Q7JNG6 protein_id:AAC71110.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE19466 WBGene00006805 locus:unc-73 status:Confirmed UniProt:Q7JNG6 protein_id:CCD63878.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] Isoform of O61528, Uncharacterized protein OS=Caenorhabditis elegans GN=unc-73 PE=1 SV=1 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	928 amino acids
Gene Ontology:
Cellular Component:	axon [IDA] intracellular [IEA] proteinaceous extracellular matrix [IEA]
Biological Process:	Rac protein signal transduction [IC] male genitalia morphogenesis [IMP] regulation of Rho protein signal transduction [IEA] DNA repair [IEA] hermaphrodite genitalia development [IMP] regulation of locomotion [IMP] mesodermal cell migration [TAS] locomotion [IMP] embryonic development ending in birth or egg hatching [IMP][NAS] positive regulation of axon extension [IMP] cell adhesion [IEA] gamete generation [IMP] engulfment of apoptotic cell [IGI] blood coagulation [IEA] positive regulation of multicellular organism growth [IMP] regulation of vulval development [TAS] positive regulation of locomotion [IMP] neuron migration [TAS] locomotory behavior [IMP] nematode larval development [NAS] positive regulation of actin filament polymerization [IDA] oviposition [IMP ][TAS] cell migration [TAS]
Molecular Function:	guanyl-nucleotide exchange factor activity [IEA] Rho guanyl-nucleotide exchange factor activity [IEA] Rac guanyl-nucleotide exchange factor activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVIKCFTCLR KQSSEVWIVT ADFDGQVEGH LTVHKGDRVE IVEDQATDCA EYVQVVLCDQ  60
   61 PTKHGLVPAS IIAPPESGSV PDRPDDSNAS GSTVSKRKSL RRIFANSSKE RAAAANSSSS 120
  121 NNNSPATRQS TSTSSPVTAN GHTTESSTSA PIGVLSSGEP TSSNSIPSSS TPTHTVPSSV 180
  181 PATVIPIVVA EDEKAEDCLP PPMENITINN SIDEKDMNED SVAASDAVEP EVALPAKVEK 240
  241 TPEETARFKR SYVLMELVET EQDYVKDLTS VVEGYIGNLN KMDLPADLVG KDKIIFANIV 300
  301 NILEFHKTNF LKEIEKCSEN YEAAGAAFVK YERRLHTLYV TYCQNKPKSD YLLAQDDFEA 360
  361 FFADTKAKLG HKVALCDLLI KPVQRIMKYQ LLLKDILKFT ERAKDKTDTL KKALQVMHVV 420
  421 PKACDDMMQV GRLQNFDKSL SAQGKLIHQG TLQISESIAG NVQKPKDRRI FLFEQSAIIA 480
  481 DHIPPKKEFG NPTYIFKSQF MVNKMVFEPN VPDDPLRFVI KSSDPTQPTS FIANAQSQEE 540
  541 KDEWNRKMSE LLDQQKRLLA ALVDPRRYND MSSGMGDLSL GAPGGDRRGA PSSANRSAAS 600
  601 SSKKPAESPK KEGKSKSSLF SFGKKPAKSP TSPPPLDAAA AGKFQKVADD QVNLETDEKV 660
  661 KVLDVKNGYA SVKKADGTVG KCPSYFLTMS DIPGTNFAEQ IQYRREWQRR VDETDVEYGP 720
  721 SAFDTATSST DNFDVLLELT TCERPVVVED MKDIEVVEGN DVEMCPIISS HTDFTVIWHG 780
  781 PAVDSKRARI QTNQLNSRLL IKHVKKCDAG AYSVIAKNSF GVTSTVAFLS VISIPDPPTD 840
  841 FTVKISGDHE VRLKWKAESG LKYCIEYRIL DDSSPENWLI ASTNIEKTHV SLRNFARNSY 900
  901 SFRVFAYNQR VRSAPSQCIC ICFDGTEM

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: unc-73

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: