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Protein Overview: unc-73

General Information:
Name(s) found: unc-73 / CE19464 [WormBase]
Description(s) found:
Found 22 descriptions.
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  • WBGene00006805 locus:unc-73 status:Confirmed UniProt:O61528 protein_id:CCD63876.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 2488 amino acids

    Gene Ontology:
    Cellular Component: axon [IDALink to PubMed article]
    intracellular [IEALink to PubMed article]
    proteinaceous extracellular matrix [IEALink to PubMed article]
    Biological Process: Rac protein signal transduction [ICLink to PubMed article]
    male genitalia morphogenesis [IMP]
    regulation of Rho protein signal transduction [IEALink to PubMed article]
    DNA repair [IEALink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed article]
    regulation of locomotion [IMPLink to PubMed article]
    mesodermal cell migration [TASLink to PubMed article]
    locomotion [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article][NASLink to PubMed article]
    positive regulation of axon extension [IMPLink to PubMed article]
    cell adhesion [IEALink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    engulfment of apoptotic cell [IGILink to PubMed article]
    blood coagulation [IEALink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed article]
    regulation of vulval development [TASLink to PubMed article]
    positive regulation of locomotion [IMPLink to PubMed article]
    neuron migration [TASLink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    nematode larval development [NASLink to PubMed article]
    positive regulation of actin filament polymerization [IDALink to PubMed article]
    oviposition [IMPLink to PubMed articleLink to PubMed article][TASLink to PubMed article]
    cell migration [TASLink to PubMed article]
    Molecular Function: guanyl-nucleotide exchange factor activity [IEALink to PubMed article]
    Rho guanyl-nucleotide exchange factor activity [IEALink to PubMed article]
    Rac guanyl-nucleotide exchange factor activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDYDGKMTM KAEDILHVLR DGIAVLPGGR CRAGQAVIVC PSREQPVNQD NLRNVFLYLF  60
   61 EVTSKMAREK GFLVVIDMRG KQTWTNVRHI LKALSSIESS STVQVFIIKP EKFWEKQKAQ 120
  121 MSLGTWDFEV EMISFESLIK IIDSSHLPKT VGGSYPYDHD EWLELRLDLE KWIWNITEIM 180
  181 EKLESVRREI CEGEQPVDVT TANAALKKSQ HAKNSIFNVP VEGIETEGNK IATRILKPSK 240
  241 GVKNPDLEAT TPYISNLTDS LRLLKGEVAK NWEVRQMELS KVYQQKQFER DAEHMIETLR 300
  301 PYKKACERSM GDVGGCANDV VRLSAEFEQF QIAVRGMEVS VKQVFDKENH LRTIGARNQI 360
  361 TDHVAARLAE EWHLVKELME RRSAVLHNAK EFFTSAQRYF AEVPRWTAQP GVNPNDVLFN 420
  421 QESLEEAIRK HDAFWAQVEE VYAQAYDDAS KVTRALKEAD AEDNVAREHS SRLQRAHKQL 480
  481 MEKWKERQVL LHHMLAMIAF ETDVRLVVDW LEQHGEPYLR RNIHIGENVN QARSFQRNHT 540
  541 NFQRVAANTY GNVQKLHQVY QDVTKSGSKI CDVDTMHGLM TDLSAKIEKF TKIENSRELL 600
  601 LRQSVLFHTH YKELTDWYGK MGEKYKDRRI DLTVPTCDKN KERFVLETDE TAQAYAMTID 660
  661 EGKTLIEMMQ RATRVFDVDY SASVAHIQLL ISDIEDKNTQ ISSEWSPRRT LLHIASKFAM 720
  721 FEQNQFEVLE QIKSWEVDMR EMAESDSFYD KADSVLPFHK DNQQQVRNAI ADIQKSAKEL 780
  781 SQALYSQKLT DLRDKRDRVV LEAIREHVRE LEIAESRVMT YANETSMRMQ AASEVGDLRR 840
  841 ISNSVCKLID NQLSALTQLG VIPNDYNDTV QKQEELRAFR DAVQHKLKEP YDAFVIRFRE 900
  901 LMENRLANRD EVVYHNEAIQ AKYCRLMNLC EDRNKLLKSA HGCYKTYETA VLPILNQLES 960
  961 EYHSPTVTDW CAGCTSSIDA DRAAYVADLL SKHMDYKERF GKGCTYALRN GDFLLRYIRR1020
 1021 STVNQSERKR HETKIADMKN NIRERQSNIL ELWMQKKLLL EGCQSFIFIE ASAKELLEFM1080
 1081 KGEGNRKLKH FEKKGRREST DDDDEFAKFK SEVKQKKTDI QTFLMLSTNE TMSRGVHGDE1140
 1141 IDRCIEQVKD EFSRFSRRVG DCEVVLRGEN GSTQSSKDEF SLDRHSDTAI FNEKKINERR1200
 1201 EENRKMLEPM RELIQSERDY IKDLERCVNI YVKEFDQAAK NGTIPTLNPL KYEIFGNIEK1260
 1261 IFKFHNDKLL HELIKYENQP EAVGASFIVW IDLLNELYTE YCVNKEQKNH VIATPDAVSF1320
 1321 FTGIRERHGL EINNEIASLL IKPVQRITRY RLLIEQLMRS CTDKTNDLKE AYEVVCSVPR1380
 1381 KVNDLIHYNC LDLKDFKVDE LGPFVTQDTL TFWEPRAYFK GRGKERQVFL FDISIVFAKR1440
 1441 IEVSPKNIKY VIKGKPLPLS EVSIVEHVEG DTCRFGLRVG TVSSNDNRID LKANNHHTKV1500
 1501 KWVQKIRDLT AGMLPLGLGV SEAYSVGTLS TARSVSVRSG ASTSSGGENR QSQDVESLLR1560
 1561 HRYSVHSCDS EQSSEVWIVT ADFDGQVEGH LTVHKGDRVE IVEDQATDCA EYVQVVLCDQ1620
 1621 PTKHGLVPAS IIAPPESGSV PDRPDDSNAS GSTVSKRKSL RRIFANSSKE RAAAANSSSS1680
 1681 NNNSPATRQS TSTSSPVTAN GHTTESSTSA PIGVLSSGEP TSSNSIPSSS TPTHTVPSSV1740
 1741 PATVIPIVVA EDEKAEDCLP PPMENITINN SIDEKDMNED SVAASDAVEP EVALPAKVEK1800
 1801 TPEETARFKR SYVLMELVET EQDYVKDLTS VVEGYIGNLN KMDLPADLVG KDKIIFANIV1860
 1861 NILEFHKTNF LKEIEKCSEN YEAAGAAFVK YERRLHTLYV TYCQNKPKSD YLLAQDDFEA1920
 1921 FFADTKAKLG HKVALCDLLI KPVQRIMKYQ LLLKDILKFT ERAKDKTDTL KKALQVMHVV1980
 1981 PKACDDMMQV GRLQNFDKSL SAQGKLIHQG TLQISESIAG NVQKPKDRRI FLFEQSAIIA2040
 2041 DHIPPKKEFG NPTYIFKSQF MVNKMVFEPN VPDDPLRFVI KSSDPTQPTS FIANAQSQEE2100
 2101 KDEWNRKMSE LLDQQKRLLA ALVDPRRYND MSSGMGDLSL GAPGGDRRGA PSSANRSAAS2160
 2161 SSKKPAESPK KEGKSKSSLF SFGKKPAKSP TSPPPLDAAA AGKFQKVADD QVNLETDEKV2220
 2221 KVLDVKNGYA SVKKADGTVG KCPSYFLTMS DIPGTNFAEQ IQYRREWQRR VDETDVEYGP2280
 2281 SAFDTATSST DNFDVLLELT TCERPVVVED MKDIEVVEGN DVEMCPIISS HTDFTVIWHG2340
 2341 PAVDSKRARI QTNQLNSRLL IKHVKKCDAG AYSVIAKNSF GVTSTVAFLS VISIPDPPTD2400
 2401 FTVKISGDHE VRLKWKAESG LKYCIEYRIL DDSSPENWLI ASTNIEKTHV SLRNFARNSY2460
 2461 SFRVFAYNQR VRSAPSQCIC ICFDGTEM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle