Protein Overview: sca-1

General Information:
Name(s) found:	sca-1 / CE18884 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00004736 locus:sca-1 status:Confirmed UniProt:G5EEK8 protein_id:CAB07262.1 [WormBase] pir\|\|T23605 hypothetical protein K11D9.2a - Caenorhabditis elegans [NCBI NR] gi\|3878520\|emb\|CAB07262.1\| C. elegans protein K11D9.2a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|3805866\|emb\|CAA09985.1\| calcium ATPase [Caenorhabditis elegans] [NCBI NR] ref\|NP_499385.2\| membrane Calcium ATPase, Sarco-Endoplasmic Reticulum Calcium ATPase (115.5 kD) (sca-1) [Caenorhabditis elegans] [NCBI NR] gi\|17554158\|ref\|NP_499386.1\| SERCA (Sarco-Endoplasmic Reticulum Calcium ATPase) family member (sca-1) [Caenorhabditis elegans] [NCBI NR] [wormpep67.fasta] CE18884 WBGene00004736 locus:sca-1 E1-E2 ATPases status:Confirmed TR:Q9XTG6 protein_id:CAB07262.1 [wormpep150.fasta] 18884 WBGene00004736 locus:sca-1 E1-E2 ATPases status:Confirmed TR:Q9XTG6 protein_id:CAB07262.1 [wormpep130-phg-ecoli-orf-rand.fasta] membrane Calcium ATPase, Sarco-Endoplasmic Reticulum Calcium ATPase (115.5 kD) (sca-1) [Caenorhabditis elegans]gi\|3878520\|emb\|CAB07262.1\| Hypothetical protein K11D9.2a [Caenorhabditis elegans]gi\|3805866\|emb\|CAA09985.1\| calcium ATPase [Caenorhabditis ele [nrdb_11152004_Chlamydomonas] locus:sca-1 E1-E2 ATPases status:Confirmed TR:Q9XTG6 protein_id:CAB07262.1 [wormpep115.fasta.reversed] CE18884 locus:sca-1 E1-E2 ATPases status:Confirmed TR:Q9XTG6 protein_id:CAB07262.1 [wormpep80.hongbin] CE18884 WBGene00004736 locus:sca-1 E1-E2 ATPases status:Confirmed UniProt:Q9XTG6_CAEEL protein_id:CAB07262.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE18884 WBGene00004736 locus:sca-1 E1-E2 ATPases status:Confirmed UniProt:Q9XTG6_CAEEL protein_id:CAB07262.1\| [wormORF-contam.fasta] Hypothetical protein K11D9.2a [Caenorhabditis elegans] [nr-271106-contam.fasta] calcium ATPase [Caenorhabditis elegans] [nr-271106-contam.fasta] SERCA (Sarco-Endoplasmic Reticulum Calcium ATPase) family member (sca-1) [Caenorhabditis elegans] [nr-271106-contam.fasta] CE18884 WBGene00004736 locus:sca-1 E1-E2 ATPases status:Partially_confirmed TR:Q9XTG6 protein_id:CAB07262.1 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta] CE18884 WBGene00004736 locus:sca-1 E1-E2 ATPases status:Partially_confirmed UniProt:Q9XTG6 protein_id:CAB07262.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE18884 WBGene00004736 locus:sca-1 E1-E2 ATPases status:Confirmed UniProt:G5EEK8 protein_id:CAB07262.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] CE18884 WBGene00004736 locus:sca-1 status:Confirmed UniProt:G5EEK8 protein_id:CAB07262.1 [wormpep246-ecoli-contam.fasta] CE18884 WBGene00004736 locus:sca-1 status:Confirmed UniProt:G5EEK8 protein_id:CAB07262.1 Calcium-transporting ATPase [c_elegans-PRJNA13758-WS250-ecoli-contam.fasta] Calcium-transporting ATPase OS=Caenorhabditis elegans GN=sca-1 PE=1 SV=1 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	1059 amino acids
Gene Ontology:
Cellular Component:	nuclear membrane-endoplasmic reticulum network [IDA] membrane [IEA] integral to membrane [IEA] endoplasmic reticulum [IDA][IEA]
Biological Process:	embryonic development [IMP] dauer larval development [IGI] proton transport [IEA] monovalent inorganic cation transport [IEA] magnesium ion transport [IEA] determination of adult lifespan [IMP] embryonic development ending in birth or egg hatching [IMP ] metabolic process [IEA] transport [IEA] reproduction [IMP ] growth [IMP ] cellular calcium ion homeostasis [IMP] potassium ion transport [IEA] cation transport [IEA] endoplasmic reticulum unfolded protein response [IGI] nematode larval development [IMP ] calcium ion transport [IEA] phospholipid transport [IEA] metal ion transport [IEA]
Molecular Function:	ATPase activity [IEA] chromatin DNA binding [IPI] magnesium-importing ATPase activity [IEA] ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism [IEA] monovalent inorganic cation transmembrane transporter activity [IEA] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [IEA] calcium ion transmembrane transporter activity [IEA] metal ion transmembrane transporter activity [IEA] phospholipid-translocating ATPase activity [IEA] calcium-transporting ATPase activity [IEA] potassium-transporting ATPase activity [IEA] magnesium ion binding [IEA] ATP binding [IEA] copper-exporting ATPase activity [IEA] catalytic activity [IEA] metal ion binding [IEA] calcium ion binding [IEA] hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDAHAKDAN EVCKFFGTGP EGLTPQQVET LRNKYGENEM PAEEGKSLWE LILEQFDDLL  60
   61 VKILLLAAII SFVLALFEEH EDQTEAVTAF VEPFVILLIL IANATVGVWQ ERNAESAIEA 120
  121 LKEYEPEMAK VIRSGHHGIQ MVRAKELVPG DLVEVSVGDK IPADLRLVKI YSTTIRIDQS 180
  181 ILTGESVSVI KHTDSVPDPR AVNQDKKNCL FSGTNVASGK ARGIVFGTGL TTEIGKIRTE 240
  241 MAETENEKTP LQQKLDEFGE QLSKVISVIC VAVWAINIGH FNDPAHGGSW VKGAIYYFKI 300
  301 AVALAVAAIP EGLPAVITTC LALGTRRMAK KNAIVRSLPS VETLGCTSVI CSDKTGTLTT 360
  361 NQMSVSKMFI AGQASGDNIN FTEFAISGST YEPVGKVSTN GREINPAAGE FESLTELAMI 420
  421 CAMCNDSSVD YNETKKIYEK VGEATETALI VLAEKMNVFG TSKAGLSPKE LGGVCNRVIQ 480
  481 QKWKKEFTLE FSRDRKSMSA YCFPASGGSG AKMFVKGAPE GVLGRCTHVR VNGQKVPLTS 540
  541 AMTQKIVDQC VQYGTGRDTL RCLALGTIDT PVSVSNMNLE DSTQFVKYEQ DITFVGVVGM 600
  601 LDPPRTEVSD SIKACNHAGI RVIMITGDNK NTAEAIGRRI GLFGENEDTT GKAYTGREFD 660
  661 DLPPEQQSEA CRRAKLFARV EPSHKSKIVD ILQSQGEITA MTGDGVNDAP ALKKAEIGIS 720
  721 MGSGTAVAKS ASEMVLADDN FASIVSAVEE GRAIYNNMKQ FIRYLISSNV GEVVSIFMVA 780
  781 ALGIPEALIP VQLLWVNLVT DGLPATALGF NPPDLDIMDR HPRSANDGLI SGWLFFRYLA 840
  841 VGTYVGVATV GASMWWFLLY EEGPQITYYQ LTHWMRCEIE PDNFADLDCA VFEDNHPNAM 900
  901 ALSVLVTIEM LNAINSLSEN QSLLVMPPWK NIWLMAAISL SMSLHFVILY VDIMATIFQI 960
  961 TPLNWVEWIA VLKISLPVLL LDEILKFIAR NYIDGKPETV GAKARSAISL LAWVSVTLAY1020
 1021 FAWMLGPYAE LINHALVGPS VDPSKFDAVV TPDKLHNEL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: sca-1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: