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Protein Overview: prmt-2

General Information:
Name(s) found: prmt-2 / CE16546 [WormBase]
Description(s) found:
Found 18 descriptions.
SHOW ALL
  • WBGene00012298 locus:prmt-2 status:Partially_confirmed UniProt:Q9XW42 protein_id:CAA22252.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 630 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: protein amino acid methylation [IEALink to PubMed article]
    Molecular Function: protein methyltransferase activity [IEALink to PubMed article]
    methyltransferase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFLEKINQKT GEREWVVAEE DYDMAQELAR SRFGDMILDF DRNDKFLAGL KTTIAEKKHE  60
   61 NTDGKVHVLD IGTGTGLLSL MAAREGADKV TALEVFKPMG DCARHITSNS PWSDKITVIS 120
  121 ERSTDVSQIG GSRADIIVAE VFDTELIGEG ALRTFKEALE RLAKPGCRVV PSTGNVYIVP 180
  181 VESHLLKMFN DIPRLNGEKD EEPLGRCSGT AAVFDVQLSE MKTHEFRELS EPIVAFKFDF 240
  241 EHEEKIIFDE SFVREAVAHS SGTIDALLMW WDIDMDRNGT TFIDMGPKWK NKNNYALMVQ 300
  301 QCWERVCIYS RNTNFYQLLF FSKSRSYCVC GLHSMLSRQT VYHVNEMFEN QKFKDEVDKL 360
  361 SKGLHVATVG EGSFLGLLAA KTAKRVTIID GNERFRDIFF KYIHYYKLTN VEIIEKVTSL 420
  421 TDSPDIVLAE PFYMSAMNPW NHLRFLYDVE VLKMMHGDEL RVEPHMGVLK AIPEKFEDLQ 480
  481 NIASDVGTVN GFDLSFFDEI STKARTATDA IVDEQSLWEY AGIVKGDAVE ILRFPIDGRV 540
  541 SSQKCVVNID NMSSSNAIPM WMEWEFGGIN LSTGLLSISS AGVPEWNKGY KQGVYFPITA 600
  601 LRNDKSLCLH ALFDKSTGDI NFQFGKSEDS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..296] PSI-BLAST 35.0 CmaA1
    2 View Details [297..630] PSI-BLAST 77.522879 Structure of the Predominant protein arginine methyltransferase PRMT1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • arginine N-methyltransferase activity
    		•  5.52520020727046 bayes_pls_golite062009
  • protein-arginine N-methyltransferase activity
    		•  5.52520020727046 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  5.03267617653315 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  4.4632173842967 bayes_pls_golite062009
  • histone methyltransferase activity (H4-R3 specific)
    		•  4.42061797259061 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  4.40911163698179 bayes_pls_golite062009
  • protein-arginine omega-N monomethyltransferase activity
    		•  4.39379274790202 bayes_pls_golite062009
  • methyltransferase activity
    		•  4.15445027778357 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  4.07806017452628 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  4.07153733729662 bayes_pls_golite062009
  • protein-arginine omega-N symmetric methyltransferase activity
    		•  3.87145704230189 bayes_pls_golite062009
  • DNA-methyltransferase activity
    		•  3.6879779213105 bayes_pls_golite062009
  • protein-arginine omega-N asymmetric methyltransferase activity
    		•  3.55785970363721 bayes_pls_golite062009
  • transferase activity
    		•  2.926540904444 bayes_pls_golite062009
  • histone-arginine N-methyltransferase activity
    		•  2.86617323549909 bayes_pls_golite062009
  • [myelin basic protein]-arginine N-methyltransferase activity
    		•  2.48953871767053 bayes_pls_golite062009
  • site-specific DNA-methyltransferase (adenine-specific) activity
    		•  1.99067501725601 bayes_pls_golite062009
  • RNA methyltransferase activity
    		•  1.86200407013263 bayes_pls_golite062009
  • rRNA methyltransferase activity
    		•  1.79395300104934 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.55725596651484 bayes_pls_golite062009
  • DNA (cytosine-5-)-methyltransferase activity
    		•  1.55340762301836 bayes_pls_golite062009
  • binding
    		•  1.54733751399119 bayes_pls_golite062009
  • histone methyltransferase activity (H2A-R3 specific)
    		•  1.49229188826344 bayes_pls_golite062009
  • histone methyltransferase activity (H3-R2 specific)
    		•  1.49229188826344 bayes_pls_golite062009
  • DNA binding
    		•  1.46895871345911 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.31440474302645 bayes_pls_golite062009
  • catalytic activity
    		•  1.25333584501255 bayes_pls_golite062009
  • RNA binding
    		•  1.10729923226801 bayes_pls_golite062009
  • histone binding
    		•  0.964746527369069 bayes_pls_golite062009
  • tRNA methyltransferase activity
    		•  0.868107614027708 bayes_pls_golite062009
  • protein-lysine N-methyltransferase activity
    		•  0.858129308056814 bayes_pls_golite062009
  • lysine N-methyltransferase activity
    		•  0.858129308056814 bayes_pls_golite062009
  • histone-lysine N-methyltransferase activity
    		•  0.858129308056814 bayes_pls_golite062009
  • mRNA methyltransferase activity
    		•  0.73490663449605 bayes_pls_golite062009
  • mRNA (guanine-N7-)-methyltransferase activity
    		•  0.73490663449605 bayes_pls_golite062009
  • rRNA (adenine) methyltransferase activity
    		•  0.102141401712309 bayes_pls_golite062009
  • rRNA (adenine-N6,N6-)-dimethyltransferase activity
    		•  0.0251895714734512 bayes_pls_golite062009
    2
    Term Confidence Notes
  • arginine N-methyltransferase activity
    		•  5.52520020727046 bayes_pls_golite062009
  • protein-arginine N-methyltransferase activity
    		•  5.52520020727046 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  5.03267617653315 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  4.4632173842967 bayes_pls_golite062009
  • histone methyltransferase activity (H4-R3 specific)
    		•  4.42061797259061 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  4.40911163698179 bayes_pls_golite062009
  • protein-arginine omega-N monomethyltransferase activity
    		•  4.39379274790202 bayes_pls_golite062009
  • methyltransferase activity
    		•  4.15445027778357 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  4.07806017452628 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  4.07153733729662 bayes_pls_golite062009
  • protein-arginine omega-N symmetric methyltransferase activity
    		•  3.87145704230189 bayes_pls_golite062009
  • DNA-methyltransferase activity
    		•  3.6879779213105 bayes_pls_golite062009
  • protein-arginine omega-N asymmetric methyltransferase activity
    		•  3.55785970363721 bayes_pls_golite062009
  • transferase activity
    		•  2.926540904444 bayes_pls_golite062009
  • histone-arginine N-methyltransferase activity
    		•  2.86617323549909 bayes_pls_golite062009
  • [myelin basic protein]-arginine N-methyltransferase activity
    		•  2.48953871767053 bayes_pls_golite062009
  • site-specific DNA-methyltransferase (adenine-specific) activity
    		•  1.99067501725601 bayes_pls_golite062009
  • RNA methyltransferase activity
    		•  1.86200407013263 bayes_pls_golite062009
  • rRNA methyltransferase activity
    		•  1.79395300104934 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.55725596651484 bayes_pls_golite062009
  • DNA (cytosine-5-)-methyltransferase activity
    		•  1.55340762301836 bayes_pls_golite062009
  • binding
    		•  1.54733751399119 bayes_pls_golite062009
  • histone methyltransferase activity (H2A-R3 specific)
    		•  1.49229188826344 bayes_pls_golite062009
  • histone methyltransferase activity (H3-R2 specific)
    		•  1.49229188826344 bayes_pls_golite062009
  • DNA binding
    		•  1.46895871345911 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.31440474302645 bayes_pls_golite062009
  • catalytic activity
    		•  1.25333584501255 bayes_pls_golite062009
  • RNA binding
    		•  1.10729923226801 bayes_pls_golite062009
  • histone binding
    		•  0.964746527369069 bayes_pls_golite062009
  • tRNA methyltransferase activity
    		•  0.868107614027708 bayes_pls_golite062009
  • protein-lysine N-methyltransferase activity
    		•  0.858129308056814 bayes_pls_golite062009
  • lysine N-methyltransferase activity
    		•  0.858129308056814 bayes_pls_golite062009
  • histone-lysine N-methyltransferase activity
    		•  0.858129308056814 bayes_pls_golite062009
  • mRNA methyltransferase activity
    		•  0.73490663449605 bayes_pls_golite062009
  • mRNA (guanine-N7-)-methyltransferase activity
    		•  0.73490663449605 bayes_pls_golite062009
  • rRNA (adenine) methyltransferase activity
    		•  0.102141401712309 bayes_pls_golite062009
  • rRNA (adenine-N6,N6-)-dimethyltransferase activity
    		•  0.0251895714734512 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle