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Protein Overview: tba-7

General Information:
Name(s) found: tba-7 / CE16521 [WormBase]
Description(s) found:
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  • WBGene00006533 locus:tba-7 status:Confirmed UniProt:O18154 protein_id:CAB03447.1 [WormBase]
  • pir||T25413 hypothetical protein T28D6.2 - Caenorhabditis elegans [NCBI NR]
  • gi|3880320|emb|CAB03447.1| C. elegans protein T28D6.2, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|17555336|ref|NP_499463.1| TuBulin, Alpha family member (tba-7) [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE16521 WBGene00006533 locus:tba-7 tubulin alpha subunit status:Confirmed TR:O18154 protein_id:CAB03447.1 [wormpep150.fasta]
  • 16521 WBGene00006533 locus:tba-7 tubulin alpha subunit status:Partially_confirmed TR:O18154 protein_id:CAB03447.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • TuBulin, Alpha (49.6 kD) (tba-7) [Caenorhabditis elegans]gi|3880320|emb|CAB03447.1| Hypothetical protein T28D6.2 [Caenorhabditis elegans]gi|7508664|pir||T25413 hypothetical protein T28D6.2 - Caenorhabditis elegans [nrdb_11152004_Chlamydomonas]
  • CE16521 WBGene00006533 locus:tba-7 tubulin alpha subunit status:Partially_confirmed TR:O18154 protein_id:CAB03447.1 [wormpep132.fasta]
  • 16521 WBGene00006533 locus:tba-7 tubulin alpha subunit status:Confirmed TR:O18154 protein_id:CAB03447.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • locus:tba-7 tubulin alpha subunit status:Partially_confirmed TR:O18154 protein_id:CAB03447.1 [wormpep115.fasta.reversed]
  • CE16521 locus:tba-7 tubulin alpha subunit status:Partially_confirmed TR:O18154 protein_id:CAB03447.1 [wormpep80.hongbin]
  • CE16521 WBGene00006533 locus:tba-7 tubulin alpha subunit status:Confirmed UniProt:O18154_CAEEL protein_id:CAB03447.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE16521 WBGene00006533 locus:tba-7 tubulin alpha subunit status:Confirmed UniProt:O18154_CAEEL protein_id:CAB03447.1| [wormORF-contam.fasta]
  • Hypothetical protein T28D6.2 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • TuBulin, Alpha family member (tba-7) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE16521 WBGene00006533 locus:tba-7 tubulin alpha subunit status:Confirmed UniProt:O18154 protein_id:CAB03447.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE16521 WBGene00006533 locus:tba-7 status:Confirmed UniProt:O18154 protein_id:CAB03447.1 [wormpep246-ecoli-contam.fasta]
  • TuBulin, Alpha OS=Caenorhabditis elegans GN=tba-7 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 444 amino acids

    Gene Ontology:
    Cellular Component: protein complex [IEALink to PubMed article]
    microtubule [IEALink to PubMed article]
    Biological Process: protein polymerization [IEALink to PubMed article]
    microtubule-based process [IEALink to PubMed article]
    Molecular Function: GTP binding [IEALink to PubMed article]
    GTPase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MREVISIHVG QAGVQIGNAC WELYCLEHGI LPDGTSMEPD GNSGSLGTFF SDTGYGRHVP  60
   61 RSIFVDLEPT VVDEIRTGAY KKLFHPEQML TGKEDAANNY ARGHYTVGKE IIDTTLDRIR 120
  121 RLANNCEGLQ GFFVFHSFGG GTGSGFTSML MERLSAEYGK KSKLEFSIYP APQISTSVVE 180
  181 PYNSILTTHT TLEHSDCSFM VDNEAIYDIC RRNLRVSRPT YNNLNRIISQ VVSSITASLR 240
  241 FDGALNVDLN EFQTNLVPYP RIHFPLVAYN PLISSAHHEF LSVDEITKSC FEASNQMVKC 300
  301 DPKHGKYMAV CLLYRGDVVP KDVSAAIKSI KTQRSVQFVD WCPTGFKVGL NYQPPTVIPG 360
  361 GDMAKVPRAV CMLSNTTAIA EAWQRLDYKF DLMYAKRAFV HWYVGEGMEE GEFSEAREDL 420
  421 AALEKDYEEV GADSDANDNG DDEY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-1 hcp1 IP from december2004 Cheeseman, I.M., et al. (2005)
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..444] PSI-BLAST 170.0 Tubulin-colchicine-vinblastine: stathmin-like domain complex

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • structural constituent of cytoskeleton
    		•  4.04224160177678 bayes_pls_golite062009
  • structural molecule activity
    		•  3.32779015200848 bayes_pls_golite062009
  • tubulin binding
    		•  2.4432045213385 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.24606230377981 bayes_pls_golite062009
  • binding
    		•  2.00508289492248 bayes_pls_golite062009
  • GTPase activity
    		•  1.87512665946067 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  1.77500173070686 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.7017047947554 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.68267378160702 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.68038087466376 bayes_pls_golite062009
  • protein binding
    		•  1.60795853516357 bayes_pls_golite062009
  • MHC class I protein binding
    		•  1.46574865275013 bayes_pls_golite062009
  • gamma-tubulin binding
    		•  1.02742779831447 bayes_pls_golite062009
  • hydrolase activity
    		•  0.502038132260603 bayes_pls_golite062009
  • receptor binding
    		•  0.00945891657658993 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.84

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle