Protein Overview: pde-1

General Information:
Name(s) found:	pde-1 / CE16340 [WormBase]
Description(s) found: Found 24 descriptions. SHOW ALL	WBGene00011433 locus:pde-1 Probable 3',5'-cyclic phosphodiesterase pde-1 status:Partially_confirmed UniProt:O18696 protein_id:CAB03289.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	664 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	signal transduction [IEA]
Molecular Function:	catalytic activity [IEA] 3',5'-cyclic-nucleotide phosphodiesterase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRARKTSSC GCFRSAFCLL KPSTSSASEE HGDSDKKLLS VQLITPRDEE EQTSSRSIKI  60
   61 PPLDLNGLDC KKNAVAARRA GRRRTSEGGG VRGKGHFAEV VLDGLQRPVS LLRNQKEKSN 120
  121 SDDNCQEKEP TSPSSSRKKS YDNAPALESL EKLRYILHQL NSGQLPLEDL KRNIEYAALV 180
  181 LETAYMDETR RICDEDDDLA EVTPETVPDE VREWLAATFT RQNAGKKRDK PKFKSVANAI 240
  241 RTGIFFEKLF RKQQVVQCPI PPEIAELMKE VCTWSFSPFQ LNEVSEGHAL KYVGFELFNR 300
  301 YGFMDRFKVP LTALENYLSA LEVGYSKHNN PYHNVVHAAD VTQSSHFMLS QTGLANSLGD 360
  361 LELLAVLFGA LIHDYEHTGH TNNFHIQSQS QFAMLYNDRS VLENHHVSSC FRLMKEDDKN 420
  421 ILTHLTRDEY KELRNMVIEI VLATDMSTHF MQIKTMKSML SLPEGIDKNK ALCLIVHACD 480
  481 ISHPAKPWNL HERWTEGVLE EFFRQGDLEA SMGLPYSPLC DRHTVHVADS QIGFIDFIVE 540
  541 PTMVVCGELL VKMVEPLVSL PPTDSLFPPS VDGGDDKSPS NALSPLPDLR NSSTSPSSIR 600
  601 RIPLNYAGKL DIPTPWMKFL HENKAHWKER AAKEEEERKI KEAAEAEAAA KQVEENKENG 660
  661 VTTN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
3',5'-cyclic-GMP phosphodiesterase activity	4.00066983687916	bayes_pls_golite062009
3',5'-cyclic-nucleotide phosphodiesterase activity	3.67241800633934	bayes_pls_golite062009
cyclic-nucleotide phosphodiesterase activity	3.66153187976312	bayes_pls_golite062009
phosphoric diester hydrolase activity	3.35655066482707	bayes_pls_golite062009
3',5'-cyclic-AMP phosphodiesterase activity	2.18711955312275	bayes_pls_golite062009
hydrolase activity	1.17086565360856	bayes_pls_golite062009
catalytic activity	1.07048165010262	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.98531713516841	bayes_pls_golite062009
binding	0.585341229695032	bayes_pls_golite062009
phosphoric ester hydrolase activity	0.511207383357891	bayes_pls_golite062009
protein binding	0.062487758537192	bayes_pls_golite062009

Source: Reynolds et al. 2008. Manuscript submitted

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..138]	MSA	6.122989	View MSA. No confident structure predictions are available.
2	View Details	[139..252]	Pfam	29.886057	No description for PF08499.3 was found. No confident structure predictions are available.
3	View Details	[253..664]	PSI-BLAST	106.0	Catalytic Domain Of Human Phosphodiesterase 1B

Protein Overview: pde-1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: