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Protein Overview: uev-1

General Information:
Name(s) found: uev-1 / CE16008 [WormBase]
Description(s) found:
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  • WBGene00006730 locus:uev-1 status:Confirmed UniProt:O45495 protein_id:CAB07383.1 [WormBase]
  • pir||T21984 hypothetical protein F39B2.2 - Caenorhabditis elegans [NCBI NR]
  • gi|3876909|emb|CAB07383.1| C. elegans protein F39B2.2, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|17508439|ref|NP_493578.1| Ubiquitin E2 (conjugating enzyme) variant family member (uev-1) [Caenorhabditis elegans] [NCBI NR]
  • Ubiquitin-conjugating enzyme E2 variant 1 OS=Caenorhabditis elegans GN=uev-1 PE=1 SV=1 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE16008 WBGene00006730 locus:uev-1 status:Confirmed TR:O45495 protein_id:CAB07383.1 [wormpep150.fasta]
  • 16008 WBGene00006730 locus:uev-1 status:Confirmed TR:O45495 protein_id:CAB07383.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • ubiquitin E2 conjugating enzyme Variant UEV-1, yeast MMS related, Ubiquitin E2 conjugating enzyme Variant (uev-1) [Caenorhabditis elegans]gi|3876909|emb|CAB07383.1| Hypothetical protein F39B2.2 [Caenorhabditis elegans]gi|7500835|pir||T21984 hypothetical [nrdb_11152004_Chlamydomonas]
  • locus:uev-1 status:Confirmed TR:O45495 protein_id:CAB07383.1 [wormpep115.fasta.reversed]
  • CE16008 locus:mms-2 status:Confirmed TR:O45495 protein_id:CAB07383.1 [wormpep80.hongbin]
  • CE16008 WBGene00006730 locus:uev-1 status:Confirmed UniProt:O45495_CAEEL protein_id:CAB07383.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE16008 WBGene00006730 locus:uev-1 status:Confirmed UniProt:O45495_CAEEL protein_id:CAB07383.1| [wormORF-contam.fasta]
  • Ubiquitin E2 (conjugating enzyme) variant family member (uev-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein F39B2.2 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE16008 WBGene00006730 locus:uev-1 status:Confirmed UniProt:O45495 protein_id:CAB07383.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
    • Organism: Caenorhabditis elegans
    Length: 139 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: protein modification process [IEALink to PubMed article]
    ubiquitin cycle [IEALink to PubMed article]
    Molecular Function: small conjugating protein ligase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVDVPRNFRL LEELEEGQKG KGDGNISWGL EDDSDMTLTR WTASIIGPPR TPYESRIYNL  60
   61 QIQCGGNYPR EPPTVRFTTK VHMVGVNQSN GVIDKRNLTT LRNWSNSYMI KTVLEDIRKN 120
  121 MMMAKENLKL QQPAEGAMF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..139] PSI-BLAST 35.39794 Structure of the human ubiquitin-conjugating enzyme E2 variant 1 (UEV-1)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  7.07009148420636 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  7.03976510657099 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  6.00007452476109 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  5.06177413452771 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.9559492182519 bayes_pls_golite062009
  • ligase activity
    		•  1.88059319399119 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.83472092683523 bayes_pls_golite062009
  • DNA binding
    		•  1.77393825735008 bayes_pls_golite062009
  • binding
    		•  1.75350658654805 bayes_pls_golite062009
  • catalytic activity
    		•  0.891402822028799 bayes_pls_golite062009
  • SUMO ligase activity
    		•  0.843488104298821 bayes_pls_golite062009
  • protein binding
    		•  0.726328463755484 bayes_pls_golite062009
  • NEDD8 ligase activity
    		•  0.715654744941217 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.58835335751383 bayes_pls_golite062009
  • kinase activity
    		•  0.519703305315987 bayes_pls_golite062009
  • protein kinase activity
    		•  0.443948654247666 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.373779304908933 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.182854082413338 bayes_pls_golite062009
  • transferase activity
    		•  0.0984525836903841 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle