Protein Overview: CE14750

General Information:
Name(s) found:	CE14750 [WormBase]
Description(s) found: Found 22 descriptions. SHOW ALL	WBGene00021112 Probable DNA-directed RNA polymerase III subunit RPC6 status:Partially_confirmed UniProt:P91529 protein_id:CCD64234.1 [WormBase]
Organism:	Caenorhabditis elegans
Length:	296 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA]
Biological Process:	transcription [IEA] reproduction [IMP]
Molecular Function:	DNA binding [IEA] DNA-directed RNA polymerase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASIKEELIS AAESESQVMQ IVQAALEGID MDALTSMTPG LPQTVRQTAI NSLLSSKKLA  60
   61 IQQAPGGVLR LKVNTSEQIA GTEEEQVIYS LIEESKTRGI WIKELREGSG LNQLQLRKTL 120
  121 KSLETKKLIK TIKAVGTTRK CYILFSIEPD MSLTGGTFYS DQQLDSELIN TLISVCGSYA 180
  181 ASRRKHAIDE NPNNIQMQRE ASYIRPQEIA QFITEKRVLN VPLSLEDLER ILEVAVLDGT 240
  241 IERRADGKIR ACPPRSSISP LVSVPCAICP VVEDCRPGYV ISPQSCDYMK NWLADL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..79]	PSI-BLAST	18.221849	No description for 2dk8A was found.
2	View Details	[80..145]	PSI-BLAST	25.30103	No description for 2dk5A was found.
3	View Details	[146..296]	Pfam	22.769551	No description for PF05158.3 was found. No confident structure predictions are available.

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
transcription regulator activity	5.55329976718261	bayes_pls_golite062009
DNA binding	5.08959163553491	bayes_pls_golite062009
nucleic acid binding	4.99681957904233	bayes_pls_golite062009
RNA polymerase activity	4.38040357248614	bayes_pls_golite062009
DNA-directed RNA polymerase activity	4.38040357248614	bayes_pls_golite062009
transcription factor activity	4.33152142980289	bayes_pls_golite062009
binding	3.52874320222492	bayes_pls_golite062009
nucleotidyltransferase activity	2.80876790343695	bayes_pls_golite062009
sequence-specific DNA binding	2.48053910222825	bayes_pls_golite062009
transcription activator activity	2.37668609508629	bayes_pls_golite062009
transcription repressor activity	2.22485867684613	bayes_pls_golite062009
transferase activity	2.17455387041569	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.13327310661537	bayes_pls_golite062009
RNA polymerase II transcription factor activity	1.70025468248325	bayes_pls_golite062009
transcription factor binding	0.85714789329232	bayes_pls_golite062009
protein binding	0.753698599635855	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	0.461477365615935	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	0.0856082199488197	bayes_pls_golite062009

2

Term	Confidence	Notes
transcription regulator activity	5.55329976718261	bayes_pls_golite062009
DNA binding	5.08959163553491	bayes_pls_golite062009
nucleic acid binding	4.99681957904233	bayes_pls_golite062009
RNA polymerase activity	4.38040357248614	bayes_pls_golite062009
DNA-directed RNA polymerase activity	4.38040357248614	bayes_pls_golite062009
transcription factor activity	4.33152142980289	bayes_pls_golite062009
binding	3.52874320222492	bayes_pls_golite062009
nucleotidyltransferase activity	2.80876790343695	bayes_pls_golite062009
sequence-specific DNA binding	2.48053910222825	bayes_pls_golite062009
transcription activator activity	2.37668609508629	bayes_pls_golite062009
transcription repressor activity	2.22485867684613	bayes_pls_golite062009
transferase activity	2.17455387041569	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.13327310661537	bayes_pls_golite062009
RNA polymerase II transcription factor activity	1.70025468248325	bayes_pls_golite062009
transcription factor binding	0.85714789329232	bayes_pls_golite062009
protein binding	0.753698599635855	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	0.461477365615935	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	0.0856082199488197	bayes_pls_golite062009

3

No functions predicted.

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle