YRC Public Data Repository - Protein Structure Prediction

Protein:	CE14750
Organism:	Caenorhabditis elegans
Length:	296 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE14750.

Description	E-value	Query Range	Subject Range
gi\|157821329, gi... - gi\|62645964\|ref\|XP_230642.2\| PREDICTED: similar to DNA-directed RNA polymerase III 39 kDa polypeptid...	402.0	[0..10]	[293..69]
gi\|50756109 - gi\|50756109\|ref\|XP_415021.1\| PREDICTED: similar to DNA-directed RNA polymerases III 39 kDa polypepti...	399.0	[0..3]	[293..35]
gi\|149733397 - gi\|149733397\|ref\|XP_001490686.1\| PREDICTED: similar to polymerase (RNA) III (DNA directed) polypepti... gi\|208967094, gi... - gi\|208967094\|dbj\|BAG73561.1\| polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa [synthetic co... ENSPTRT00000024694 - null POLR3F - polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa	396.0	[0..10]	[293..14]
gi\|39794390, gi\|... - gi\|45361485\|ref\|NP_989319.1\| polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa [Xenopus (Sil...	395.0	[0..2]	[293..4]
gi\|57104040 - gi\|57104040\|ref\|XP_534333.1\| PREDICTED: similar to DNA-directed RNA polymerase III 39 kDa polypeptid...	394.0	[0..10]	[293..14]
gi\|126035615 - gi\|126035615\|gb\|ABN72532.1\| DNA-directed RNA polymerase III polypeptide F [Mus spretus] RPC6_MOUSE - DNA-directed RNA polymerase III subunit RPC6 OS=Mus musculus GN=Polr3f PE=1 SV=1	393.0	[0..10]	[293..14]
RPC6_BOVIN - DNA-directed RNA polymerase III subunit RPC6 OS=Bos taurus GN=POLR3F PE=2 SV=1	392.0	[0..10]	[293..14]
gi\|114681155 - gi\|114681155\|ref\|XP_001141647.1\| PREDICTED: DNA-directed RNA polymerase III 39 kDa polypeptide F iso...	391.0	[0..10]	[293..14]

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Predicted Domain #1

Region A:
Residues: [1-79]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASIKEELIS AAESESQVMQ IVQAALEGID MDALTSMTPG LPQTVRQTAI NSLLSSKKLA  60
   61 IQQAPGGVLR LKVNTSEQI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	18.221849
Match:	2dk8A
Description:	No description for 2dk8A was found.

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	5.55329976718261	bayes_pls_golite062009
DNA binding	5.08959163553491	bayes_pls_golite062009
nucleic acid binding	4.99681957904233	bayes_pls_golite062009
RNA polymerase activity	4.38040357248614	bayes_pls_golite062009
DNA-directed RNA polymerase activity	4.38040357248614	bayes_pls_golite062009
transcription factor activity	4.33152142980289	bayes_pls_golite062009
binding	3.52874320222492	bayes_pls_golite062009
nucleotidyltransferase activity	2.80876790343695	bayes_pls_golite062009
sequence-specific DNA binding	2.48053910222825	bayes_pls_golite062009
transcription activator activity	2.37668609508629	bayes_pls_golite062009
transcription repressor activity	2.22485867684613	bayes_pls_golite062009
transferase activity	2.17455387041569	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.13327310661537	bayes_pls_golite062009
RNA polymerase II transcription factor activity	1.70025468248325	bayes_pls_golite062009
transcription factor binding	0.85714789329232	bayes_pls_golite062009
protein binding	0.753698599635855	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	0.461477365615935	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	0.0856082199488197	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [80-145]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGTEEEQVIY SLIEESKTRG IWIKELREGS GLNQLQLRKT LKSLETKKLI KTIKAVGTTR  60
   61 KCYILF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.30103
Match:	2dk5A
Description:	No description for 2dk5A was found.

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	5.55329976718261	bayes_pls_golite062009
DNA binding	5.08959163553491	bayes_pls_golite062009
nucleic acid binding	4.99681957904233	bayes_pls_golite062009
RNA polymerase activity	4.38040357248614	bayes_pls_golite062009
DNA-directed RNA polymerase activity	4.38040357248614	bayes_pls_golite062009
transcription factor activity	4.33152142980289	bayes_pls_golite062009
binding	3.52874320222492	bayes_pls_golite062009
nucleotidyltransferase activity	2.80876790343695	bayes_pls_golite062009
sequence-specific DNA binding	2.48053910222825	bayes_pls_golite062009
transcription activator activity	2.37668609508629	bayes_pls_golite062009
transcription repressor activity	2.22485867684613	bayes_pls_golite062009
transferase activity	2.17455387041569	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.13327310661537	bayes_pls_golite062009
RNA polymerase II transcription factor activity	1.70025468248325	bayes_pls_golite062009
transcription factor binding	0.85714789329232	bayes_pls_golite062009
protein binding	0.753698599635855	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	0.461477365615935	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	0.0856082199488197	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [146-296]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SIEPDMSLTG GTFYSDQQLD SELINTLISV CGSYAASRRK HAIDENPNNI QMQREASYIR  60
   61 PQEIAQFITE KRVLNVPLSL EDLERILEVA VLDGTIERRA DGKIRACPPR SSISPLVSVP 120
  121 CAICPVVEDC RPGYVISPQS CDYMKNWLAD L

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	22.769551
Match:	PF05158.3
Description:	No description for PF05158.3 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: