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Protein Overview: nrs-2

General Information:
Name(s) found: nrs-2 / CE09642 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00003816 locus:asns-1 Asparagine synthetase status:Partially_confirmed UniProt:O16924 protein_id:CCD64106.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 551 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: locomotory behavior [IMPLink to PubMed article]
    asparagine biosynthetic process [IEALink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    metabolic process [IEALink to PubMed article]
    Molecular Function: asparagine synthase (glutamine-hydrolyzing) activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCGIWAIIGE QVTPQQQDAF MKIVGRGPDL TVLEEVQPNV HLGFHRLAIV MPGDTPSAQP  60
   61 IVGGGLSVVC NGEIYNHQSL KIDCPFTLKN GGSDCAAIIT SFIKHNKDLK EACASLDGVF 120
  121 AFIMADDKNV YIGRDPIGVR PLFYGYNSNG SLLIGSEVKC IEELCERVEY FPPGCCATIS 180
  181 LFAPTRPVQP QQYYSVPTIA DRFLSIDCTK TLVRDVLVKS VEKRLMGNRN FGFMLSGGLD 240
  241 SSLIASIATR FLKQKPIAFS VGFEDSPDLE NAKKVADYLK IPHEVLVITP QQCIDIIPEV 300
  301 VFALETFDPL IIRCGIAHYL LCQHISKSSD VKVLLSGEGA DELFGSYAYM QRAPNALHLH 360
  361 KEILRRMHHL HQYDVLRCDR STSCHGLEIR VPFLDKRFID LVSRLPPSYK LMPMKLEKHV 420
  421 LRSAFEGWLP DEVLWRSKEG FAEALGKTDL GDILAEHCDK LISKSLYERR AERFPDRTPE 480
  481 TTEEYWYRQI FEDTFVYDKM GHLVHTKVYR TAAWHRPDEK ENMHLETETL DVKTDDLLRL 540
  541 RRRSTGSLGV A

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..551] PSI-BLAST 121.0 Asparagine synthetase B, C-terminal domain; Asparagine synthetase B, N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • asparagine synthase (glutamine-hydrolyzing) activity
    		•  3.86770527955716 bayes_pls_golite062009
  • asparaginase activity
    		•  2.94567124791739 bayes_pls_golite062009
  • peptidase activity
    		•  1.76298553502805 bayes_pls_golite062009
  • DNA binding
    		•  1.66643360311025 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.65897778831304 bayes_pls_golite062009
  • endopeptidase activity
    		•  1.58381740825719 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  1.56290563467621 bayes_pls_golite062009
  • acid-ammonia (or amide) ligase activity
    		•  1.41109692769794 bayes_pls_golite062009
  • N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity
    		•  1.2528157874993 bayes_pls_golite062009
  • catalytic activity
    		•  1.19663085909195 bayes_pls_golite062009
  • binding
    		•  1.18139971903068 bayes_pls_golite062009
  • carbon-nitrogen ligase activity, with glutamine as amido-N-donor
    		•  1.17174228126736 bayes_pls_golite062009
  • hydrolase activity
    		•  1.05106912722792 bayes_pls_golite062009
  • protein binding
    		•  1.03373728327879 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.85

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle