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View Structure Prediction Details

Protein: nrs-2
Organism: Caenorhabditis elegans
Length: 551 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nrs-2.

Description E-value Query
Range
Subject
Range
gi|1778370, gi|7... - pir||T08846 asparagine synthase (glutamine-hydrolysing) (EC 6.3.5.4) - soybean, gi|1778370|gb|AAC496...
481.0 [0..1] [551..1]

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Predicted Domain #1
Region A:
Residues: [1-551]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCGIWAIIGE QVTPQQQDAF MKIVGRGPDL TVLEEVQPNV HLGFHRLAIV MPGDTPSAQP  60
   61 IVGGGLSVVC NGEIYNHQSL KIDCPFTLKN GGSDCAAIIT SFIKHNKDLK EACASLDGVF 120
  121 AFIMADDKNV YIGRDPIGVR PLFYGYNSNG SLLIGSEVKC IEELCERVEY FPPGCCATIS 180
  181 LFAPTRPVQP QQYYSVPTIA DRFLSIDCTK TLVRDVLVKS VEKRLMGNRN FGFMLSGGLD 240
  241 SSLIASIATR FLKQKPIAFS VGFEDSPDLE NAKKVADYLK IPHEVLVITP QQCIDIIPEV 300
  301 VFALETFDPL IIRCGIAHYL LCQHISKSSD VKVLLSGEGA DELFGSYAYM QRAPNALHLH 360
  361 KEILRRMHHL HQYDVLRCDR STSCHGLEIR VPFLDKRFID LVSRLPPSYK LMPMKLEKHV 420
  421 LRSAFEGWLP DEVLWRSKEG FAEALGKTDL GDILAEHCDK LISKSLYERR AERFPDRTPE 480
  481 TTEEYWYRQI FEDTFVYDKM GHLVHTKVYR TAAWHRPDEK ENMHLETETL DVKTDDLLRL 540
  541 RRRSTGSLGV A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 121.0
Match: 1ct9A
Description: Asparagine synthetase B, C-terminal domain; Asparagine synthetase B, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
asparagine synthase (glutamine-hydrolyzing) activity 3.86770527955716 bayes_pls_golite062009
asparaginase activity 2.94567124791739 bayes_pls_golite062009
peptidase activity 1.76298553502805 bayes_pls_golite062009
DNA binding 1.66643360311025 bayes_pls_golite062009
nucleic acid binding 1.65897778831304 bayes_pls_golite062009
endopeptidase activity 1.58381740825719 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 1.56290563467621 bayes_pls_golite062009
acid-ammonia (or amide) ligase activity 1.41109692769794 bayes_pls_golite062009
N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity 1.2528157874993 bayes_pls_golite062009
catalytic activity 1.19663085909195 bayes_pls_golite062009
binding 1.18139971903068 bayes_pls_golite062009
carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1.17174228126736 bayes_pls_golite062009
hydrolase activity 1.05106912722792 bayes_pls_golite062009
protein binding 1.03373728327879 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle