Protein Overview: let-502

General Information:
Name(s) found:	let-502 / CE08098 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00002694 locus:let-502 Rho-associated protein kinase let-502 status:Confirmed UniProt:P92199 protein_id:CCD64221.1 [WormBase] pir\|\|T25539 hypothetical protein C10H11.9 - Caenorhabditis elegans [NCBI NR] gi\|1825755\|gb\|AAB42348.1\| Lethal protein 502 [Caenorhabditis elegans] [NCBI NR] gi\|1816620\|gb\|AAB42081.1\| LET-502 [Caenorhabditis elegans] [NCBI NR] gi\|17508247\|ref\|NP_491440.1\| LEThal family member (let-502) [Caenorhabditis elegans] [NCBI NR] Rho-associated protein kinase let-502 OS=Caenorhabditis elegans GN=let-502 PE=1 SV=1 [Swiss-Prot] [wormpep67.fasta] CE08098 WBGene00002694 locus:let-502 Rho-associated kinase status:Confirmed TR:P92199 protein_id:AAB42348.1 [wormpep150.fasta] 08098 WBGene00002694 locus:let-502 Rho-associated kinase status:Confirmed TR:P92199 protein_id:AAB42348.1 [wormpep130-phg-ecoli-orf-rand.fasta] rho-associated kinase, LEThal LET-502 (135.8 kD) (let-502) [Caenorhabditis elegans]gi\|1825755\|gb\|AAB42348.1\| Lethal protein 502 [Caenorhabditis elegans]gi\|1816620\|gb\|AAB42081.1\| LET-502 [Caenorhabditis elegans]gi\|7495847\|pir\|\|T25539 hypothetical protei [nrdb_11152004_Chlamydomonas] locus:let-502 Rho-associated kinase status:Confirmed TR:P92199 protein_id:AAB42348.1 [wormpep115.fasta.reversed] CE08098 locus:let-502 Rho-associated kinase status:Confirmed [wormpep80.hongbin] CE08098 WBGene00002694 locus:let-502 Rho-associated kinase status:Confirmed UniProt:P92199_CAEEL protein_id:AAB42348.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE08098 WBGene00002694 locus:let-502 Rho-associated kinase status:Confirmed UniProt:P92199_CAEEL protein_id:AAB42348.1\| [wormORF-contam.fasta] Lethal protein 502 [Caenorhabditis elegans] [nr-271106-contam.fasta] LET-502 [Caenorhabditis elegans] [nr-271106-contam.fasta] LEThal family member (let-502) [Caenorhabditis elegans] [nr-271106-contam.fasta] CE08098 WBGene00002694 locus:let-502 Rho-associated kinase status:Confirmed UniProt:P92199 protein_id:AAB42348.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE08098 WBGene00002694 locus:let-502 Rho-associated kinase status:Confirmed UniProt:P92199 protein_id:CCD64221.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] CE08098 WBGene00002694 locus:let-502 status:Confirmed UniProt:P92199 protein_id:CCD64221.1 Rho-associated protein kinase let-502 [wormpep246-ecoli-contam.fasta]
Organism:	Caenorhabditis elegans
Length:	1173 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] contractile fiber [IDA] cytoplasm [IDA] cell-cell adherens junction [IDA]
Biological Process:	embryonic development [IMP] regulation of cell shape [IMP] collagen and cuticulin-based cuticle development [IMP ] embryonic development ending in birth or egg hatching [IMP ] post-embryonic body morphogenesis [IMP] Rho protein signal transduction [TAS] protein amino acid phosphorylation [IEA][ISS] positive regulation of multicellular organism growth [IMP ] reproduction [IMP] growth [IMP] nematode larval development [IMP ] gastrulation with mouth forming first [IMP] cell migration [IMP ]
Molecular Function:	magnesium ion binding [IEA] ATP binding [IEA][ISS] protein tyrosine kinase activity [IEA] zinc ion binding [IEA] protein kinase activity [IEA] protein serine/threonine kinase activity [IEA][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQDELRDQL VDPKSPINIE SLLDTITALV NDCKIPVLMR MKSVDNFISR YERVVESLAA  60
   61 LRMKAADFRQ LKVIGRGAFG EVHLVRHTRT NTVYAMKMLN KDDMIKRADS AFFWEERDIM 120
  121 AHANSEWIVR LQYAFQDPRH LYMVMEYMPG GDLVNLMTSY EVSEKWTRFY TAEIVEALAA 180
  181 LHSMGYIHRD VKPDNMLISI SGHIKLADFG TCVKMNANGV VRCSTAVGTP DYISPEVLRN 240
  241 QGQDAEFGKE VDWWSVGVFI YEMLVGETPF YAEALVSTYT NIMNHKTSLK FPDEPLISTQ 300
  301 AKDIIKKFLS AAPDRLGRNS VDDIRNHKFF VNDEWTFATL REASPPVIPS LKSDDDTTHF 360
  361 EEIETRDRDN AGDFQLPKTF NGNQLPFIGF TYSNEYSPVK NLLKGHGAGS KQNGIEQHKP 420
  421 QTVVEQPLTN GHASGVPEEK YEAVKMELDS KNREFELLKD SIARNEIRAK MIENEKNSLS 480
  481 TKISDLEREL KDNKDKLRHG ADSDAKVNEL AVELRMSKEY NSEMESELSK FRDKCEQLKE 540
  541 DLRKKSGELA QEKNETQRVF QQKKDADEAF AEIKRDYELL QTRENEKSVQ LKKALDERKE 600
  601 NGAYQQSVAK ATDAEWERKM QFYEKQLEHA NDERKREEQK RTAAEFDQSR VARKLAGIEA 660
  661 NYELLQNDYK SMKEARKDLE RDLQDVITEK RRLEIRVEQL MDSRNTDERV LSLCQDELVE 720
  721 SQEEAKYKED GLRGKIDGFK HELENEKMKT QTLEENLLVA DKERGMLKME VQELMQRHKW 780
  781 EITNKDQTLK HLETQLDEIK QQSKIESSEQ ESNDKQTIAD LRKKLDLEKA HKKAVINKLE 840
  841 EEMAKRQPLK KGEKGVTKSA LIKKEREIMA LEQERDTMSK RIAALFYEND KQAEHFNIAI 900
  901 QDMQTTQDAL RDELKECKEE LANRNVNTRY EDKRSLDSRE GIPSSLSNQH IQMEGWLSLR 960
  961 DNTKKSRKPK WTNCFVALNE YSFTIYVDEK AVSVILLIEA GAMAHVRHVT AADLRNVDDS1020
 1021 QLPKIFHIMY DDASCNSSRH ASNSDLSMIE SFREESWKRH DFQELSYHIR TFCDVCNKKL1080
 1081 SDIIRPTPAF ECKNCHFKTH KDHVAQGSLP MCRYNTGLSR ELVLMAPQTD NCNKWVSQLR1140
 1141 RFIESSRSAA VSVSRVSSRR HAPGSSNSST IYQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: let-502

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: