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Protein Overview: ceh-10

General Information:
Name(s) found: ceh-10 / CE07563 [WormBase]
Description(s) found:
Found 23 descriptions.
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  • WBGene00000435 locus:ceh-10 Homeobox protein ceh-10 status:Confirmed UniProt:P41935 protein_id:CCD73324.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 344 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article][IMPLink to PubMed article]
    Biological Process: tail morphogenesis [IMPLink to PubMed article]
    neuron migration [IMPLink to PubMed article]
    locomotion [IMPLink to PubMed article]
    cell differentiation [IMPLink to PubMed article]
    oviposition [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    cell fate specification [IMPLink to PubMed article]
    regulation of cell migration [IMPLink to PubMed article]
    cell migration [IMPLink to PubMed article]
    Molecular Function: transcription factor activity [IEALink to PubMed article][TASLink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVDEMQLAA SMQMSNQMSN SQRMSFAIHE ILGIQGNAYL SHGYCPQGTF LSNQPNFMDI  60
   61 GSCGVSGFDR QLCGTDSIGN APAPLMYRMP ISTSEVITSE PQTHVSSSSI LSSATTSNSS 120
  121 GGGSSGGGGK ASKRKKRRHR TIFTQYQIDE LEKAFQDSHY PDIYAREVLA GKTELQEDRI 180
  181 QVWFQNRRAK WRKTEKTWGK STIMAEYGLY GAMVRHSLPL PETITKSAEA ADPQQSAAPW 240
  241 LLGMHKKSME AAAHLESVEK CDMSDSDDDD RPVTPPVQRQ VKNEYKPRII EHVQQQAPQH 300
  301 QSSLNFDTSL VVSSSLSQLH FQDSQMIPNN NASLKLYHDY NNPM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..120] deduced N/A No confident structure predictions are available.
    2 View Details [121..206] PSI-BLAST 25.154902 Paired protein
    3 View Details [207..344] MSA 8.378995 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  5.13863038737912 bayes_pls_golite062009
  • DNA binding
    		•  4.66369707598026 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.51452285155271 bayes_pls_golite062009
  • transcription factor activity
    		•  4.06706589695599 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  3.5139760613123 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.16896789933192 bayes_pls_golite062009
  • transcription activator activity
    		•  3.10621734076555 bayes_pls_golite062009
  • binding
    		•  3.02779747447702 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.91962622287073 bayes_pls_golite062009
  • protein binding
    		•  1.88087411289001 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.73068440195944 bayes_pls_golite062009
  • chromatin binding
    		•  1.68956710349366 bayes_pls_golite062009
  • transcription factor binding
    		•  1.40653841901929 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.869448556410126 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.84983974758882 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.25931464844298 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle