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Protein Overview: CE06744

General Information:
Name(s) found: CE06744 [WormBase]
Description(s) found:
Found 19 descriptions.
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  • WBGene00015298 status:Confirmed UniProt:Q17556 protein_id:CCD62406.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 631 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEALink to PubMed article]
    Biological Process: carbohydrate metabolic process [IEALink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    nucleotide-sugar metabolic process [IEALink to PubMed article]
    extracellular polysaccharide biosynthetic process [IEALink to PubMed article]
    GDP-mannose metabolic process [IEALink to PubMed article]
    oviposition [IMPLink to PubMed article]
    steroid biosynthetic process [IEALink to PubMed article]
    biosynthetic process [IEALink to PubMed article]
    galactose metabolic process [IEALink to PubMed article]
    cellular metabolic process [IEALink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: 3-beta-hydroxy-delta5-steroid dehydrogenase activity [IEALink to PubMed article]
    NADP or NADPH binding [IEALink to PubMed article]
    coenzyme binding [IEALink to PubMed article]
    catalytic activity [IEALink to PubMed article]
    UDP-glucose 4-epimerase activity [IEALink to PubMed article]
    steroid delta-isomerase activity [IEALink to PubMed article]
    dTDP-glucose 4,6-dehydratase activity [IEALink to PubMed article]
    L-aminoadipate-semialdehyde dehydrogenase activity [IEALink to PubMed article]
    ADP-glyceromanno-heptose 6-epimerase activity [IEALink to PubMed article]
    dTDP-4-dehydrorhamnose reductase activity [IEALink to PubMed article]
    GDP-mannose 4,6-dehydratase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVYTPKNVVI TGGCGFIGSN FVNYIHDAWP TCNFVNIDKL ILNSDTQNVA ESVRNSPRYK  60
   61 LVLTDIKNEA AILNVFEQNE IDTVIHFAAD CTSTRCYNET AEAVQNNVLS FIQFLETVRT 120
  121 YGKIKRFVHI STDEVYGDSD LSENEQGKVE FSRLVPGNPY AATKIAGEAY VRAYQTQYNL 180
  181 PIVTARMNNI YGPNQWDVKV VPRFIEIAKV RGEYTIQGSG KQLRSWLFVD DASAGLKAVC 240
  241 EKGELHEIYN LGTYYEKNVA DLAKTIQEEV DLQLGRAHEP PKYKSIPDRP YNDLRYLISI 300
  301 EKAKNDLGWE PTTSFDDGMR HTVASALKEH KHVKMHVAIY GGKGYVGQEL QHVLNDRHIP 360
  361 YVLATKKVGF DSDEEVEREL ALLGVTHVIC VTGRTHGPGC NTIEYLEGRA DKVFINVRDN 420
  421 MYSATILAHM CRKLGLHYTY IGTGYMFAYD KEHPIGGAEF KEEDEPTFFG SAYSVVKGFT 480
  481 DRQMNYFNQN GWENLNVRIT LPLSLDLEQP RNLLSKIIKY KELFDIPVSL TILPDCMNAM 540
  541 CNLMEQRSGG TLNLVNPEPI SLYEVVKIYK EIVDETVNPT SIGVETERAQ HLLATKGNCA 600
  601 LDTEKLQSLA PVLSAKQSLI KHFSEMTSAA K

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..339] PSI-BLAST 92.09691 dTDP-glucose 4,6-dehydratase (RmlB)
    2 View Details [340..631] PSI-BLAST 41.0 GDP-4-keto-6-deoxy-d-mannose epimerase/reductase (GDP-fucose synthetase)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • UDP-glucose 4-epimerase activity
    		•  2.13934644118967 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.03956654822048 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.868888700854563 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.82673050487418 bayes_pls_golite062009
  • DNA binding
    		•  0.790382977752475 bayes_pls_golite062009
  • binding
    		•  0.784517759335365 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.613310508772122 bayes_pls_golite062009
  • transcription factor activity
    		•  0.11102650759187 bayes_pls_golite062009
    2
    Term Confidence Notes
  • UDP-glucose 4-epimerase activity
    		•  2.13934644118967 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.03956654822048 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.868888700854563 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.82673050487418 bayes_pls_golite062009
  • DNA binding
    		•  0.790382977752475 bayes_pls_golite062009
  • binding
    		•  0.784517759335365 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.613310508772122 bayes_pls_golite062009
  • transcription factor activity
    		•  0.11102650759187 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle