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Protein Overview: dhs-12

General Information:
Name(s) found: dhs-12 / CE06157 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00000975 locus:dhs-12 status:Confirmed UniProt:G5EG13 protein_id:CAA93091.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 255 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: estrogen biosynthetic process [IEALink to PubMed article]
    tetrahydrobiopterin biosynthetic process [IEALink to PubMed article]
    poly-hydroxybutyrate biosynthetic process [IEALink to PubMed article]
    metabolic process [IEALink to PubMed article]
    Molecular Function: estradiol 17-beta-dehydrogenase activity [IEALink to PubMed article]
    sepiapterin reductase activity [IEALink to PubMed article]
    oxidoreductase activity [IEALink to PubMed article]
    NAD or NADH binding [IEALink to PubMed article]
    3-hydroxybutyrate dehydrogenase activity [IEALink to PubMed article]
    acetoacetyl-CoA reductase activity [IEALink to PubMed article]
    2-deoxy-D-gluconate 3-dehydrogenase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPKTIFITG ANRGIGLGLV RELLKVPGVE ALVAGARNID GAKELQSLAK ADARLHLIAV  60
   61 DVSNDGSLEN SVKSVSGIVG DRGLNLLINN AGLIESYGTT SAPNRASVLH CIDVNAVSAL 120
  121 LASQHFLPLL QKAASHVSGD SLTPDRAAIV NIGSDCASQA LNLRGSGPSN SLLAYKMSKV 180
  181 AMLSFSRSMA ADFKRLEIPV LITNIHPGWV QTDMGGSNAE ISVDESVTKI VASIAKLNGG 240
  241 HQGGLFNREL EEMPL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..255] PSI-BLAST 38.69897 Carbonyl reductase Sniffer of D. melanogaster

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • binding
    		•  0.982999356179965 bayes_pls_golite062009
  • DNA binding
    		•  0.302492036575815 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.177044638410302 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.150346154405223 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle