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Protein Overview: CE05666

General Information:
Name(s) found: CE05666 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00008948 Uridine kinase status:Confirmed UniProt:Q19583 protein_id:CAA93459.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 515 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: hermaphrodite genitalia development [IMPLink to PubMed article]
    uracil salvage [IEALink to PubMed article]
    biosynthetic process [IEALink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: nucleotide binding [IEALink to PubMed article]
    ATP binding [IEALink to PubMed article]
    uracil phosphoribosyltransferase activity [IEALink to PubMed article]
    uridine kinase activity [IEALink to PubMed article]
    nucleoside-triphosphatase activity [IEALink to PubMed article]
    kinase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVNQSGGDSE DSTSPRAAGC RTRRRTMSGG RAEHHLLTTK TGKKIYTKGR PPWYDKKGKS  60
   61 LKHPFVIGVC GGSASGKTTV AEKIVERLGI PWVTILSMDS FYKVLTPEEI KAAHESRYNF 120
  121 DGPNAFDFDL LYEVLKRLRE GKSVDVPVYD FNTHSRDPNS KMMYGADVLI FEGILAFHDE 180
  181 RIKNLMDMKV FVDTDGDLRL ARRIVRDVTD RGRDIDGIME QYFTFVKPAF DKYIAPCMDS 240
  241 ADLIVPRGGE NDVAIDMIVQ NVMAQLVERG YDRNQNNRDR HDLVRDDLPD CLPENLFILK 300
  301 ETPQVKGLVT FVRDRETSRD NHIFYSDRLM RILIEECMNH MPYKDVEIEM AGGRKTIGKR 360
  361 KDAQICGLPI MRAGECMETA LRSIVKDCVI GKILIQTNET TFDPELHYIR LPPHITRYKV 420
  421 IIMDATVTTG SAAMMAIRVL LDHDVKEEDI FVASLLMGQQ GAHALAYAFP KVKLITTAMD 480
  481 HQMTENCYLI PGMGNFGDRY YGTGLEQDMD EPFDM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..294] PSI-BLAST 45.221849 Crystal structure of human uridine-cytidine kinase 2 complexed with a feedback-inhibitor, CTP
    2 View Details [295..515] PSI-BLAST 54.39794 Uracil PRTase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  3.66392587433723 bayes_pls_golite062009
  • nucleotide kinase activity
    		•  2.24094813695083 bayes_pls_golite062009
  • kinase activity
    		•  2.0779386406753 bayes_pls_golite062009
  • binding
    		•  2.05253348982328 bayes_pls_golite062009
  • phosphotransferase activity, phosphate group as acceptor
    		•  1.96697952975573 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.60768715809391 bayes_pls_golite062009
  • DNA binding
    		•  1.11699929651302 bayes_pls_golite062009
  • RNA helicase activity
    		•  1.02424782546779 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.989226939888218 bayes_pls_golite062009
  • RNA-dependent ATPase activity
    		•  0.95986988363392 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
    		•  0.94128341275411 bayes_pls_golite062009
  • hydrolase activity
    		•  0.533811513387322 bayes_pls_golite062009
  • adenylate kinase activity
    		•  0.447752711852745 bayes_pls_golite062009
  • protein binding
    		•  0.193768631623192 bayes_pls_golite062009
  • nucleotide binding
    		•  0.114848452385726 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.10713474095071 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.0916519414118148 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.0915913646217636 bayes_pls_golite062009
  • helicase activity
    		•  0.0775311459068899 bayes_pls_golite062009
  • transcription factor activity
    		•  0.0434163635422169 bayes_pls_golite062009
    2
    Term Confidence Notes
  • uracil phosphoribosyltransferase activity
    		•  3.97944228585882 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  3.91023158228049 bayes_pls_golite062009
  • adenine phosphoribosyltransferase activity
    		•  3.07502596276449 bayes_pls_golite062009
  • hypoxanthine phosphoribosyltransferase activity
    		•  2.97347277288245 bayes_pls_golite062009
  • transferase activity
    		•  2.73727660668741 bayes_pls_golite062009
  • transferase activity, transferring pentosyl groups
    		•  2.53679639481311 bayes_pls_golite062009
  • catalytic activity
    		•  2.30431811394775 bayes_pls_golite062009
  • nucleobase binding
    		•  1.70525606708275 bayes_pls_golite062009
  • purine binding
    		•  1.24786927434743 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.09798789282825 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.07284130528063 bayes_pls_golite062009
  • ribose phosphate diphosphokinase activity
    		•  0.947697983706416 bayes_pls_golite062009
  • DNA binding
    		•  0.854593555814443 bayes_pls_golite062009
  • diphosphotransferase activity
    		•  0.749909396904601 bayes_pls_golite062009
  • binding
    		•  0.691442295634288 bayes_pls_golite062009
  • amidophosphoribosyltransferase activity
    		•  0.360901350940423 bayes_pls_golite062009
  • transcription factor activity
    		•  0.339219342075596 bayes_pls_golite062009
  • orotate phosphoribosyltransferase activity
    		•  0.148898393751978 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle