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View Structure Prediction Details

Protein: CE05666
Organism: Caenorhabditis elegans
Length: 515 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE05666.

Description E-value Query
Range
Subject
Range
gi|76632877 - gi|76632877|ref|XP_881396.1| PREDICTED: similar to uridine-cytidine kinase 1-like 1 isoform 9 [Bos t...
409.0 [0..5] [514..24]

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Predicted Domain #1
Region A:
Residues: [1-294]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVNQSGGDSE DSTSPRAAGC RTRRRTMSGG RAEHHLLTTK TGKKIYTKGR PPWYDKKGKS  60
   61 LKHPFVIGVC GGSASGKTTV AEKIVERLGI PWVTILSMDS FYKVLTPEEI KAAHESRYNF 120
  121 DGPNAFDFDL LYEVLKRLRE GKSVDVPVYD FNTHSRDPNS KMMYGADVLI FEGILAFHDE 180
  181 RIKNLMDMKV FVDTDGDLRL ARRIVRDVTD RGRDIDGIME QYFTFVKPAF DKYIAPCMDS 240
  241 ADLIVPRGGE NDVAIDMIVQ NVMAQLVERG YDRNQNNRDR HDLVRDDLPD CLPE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.221849
Match: 1udwA
Description: Crystal structure of human uridine-cytidine kinase 2 complexed with a feedback-inhibitor, CTP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleobase, nucleoside, nucleotide kinase activity 3.66392587433723 bayes_pls_golite062009
nucleotide kinase activity 2.24094813695083 bayes_pls_golite062009
kinase activity 2.0779386406753 bayes_pls_golite062009
binding 2.05253348982328 bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor 1.96697952975573 bayes_pls_golite062009
nucleic acid binding 1.60768715809391 bayes_pls_golite062009
DNA binding 1.11699929651302 bayes_pls_golite062009
RNA helicase activity 1.02424782546779 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
transcription regulator activity 0.989226939888218 bayes_pls_golite062009
RNA-dependent ATPase activity 0.95986988363392 bayes_pls_golite062009
ATP-dependent RNA helicase activity 0.94128341275411 bayes_pls_golite062009
hydrolase activity 0.533811513387322 bayes_pls_golite062009
adenylate kinase activity 0.447752711852745 bayes_pls_golite062009
protein binding 0.193768631623192 bayes_pls_golite062009
nucleotide binding 0.114848452385726 bayes_pls_golite062009
purine nucleotide binding 0.10713474095071 bayes_pls_golite062009
purine ribonucleotide binding 0.0916519414118148 bayes_pls_golite062009
ribonucleotide binding 0.0915913646217636 bayes_pls_golite062009
helicase activity 0.0775311459068899 bayes_pls_golite062009
transcription factor activity 0.0434163635422169 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [295-515]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLFILKETPQ VKGLVTFVRD RETSRDNHIF YSDRLMRILI EECMNHMPYK DVEIEMAGGR  60
   61 KTIGKRKDAQ ICGLPIMRAG ECMETALRSI VKDCVIGKIL IQTNETTFDP ELHYIRLPPH 120
  121 ITRYKVIIMD ATVTTGSAAM MAIRVLLDHD VKEEDIFVAS LLMGQQGAHA LAYAFPKVKL 180
  181 ITTAMDHQMT ENCYLIPGMG NFGDRYYGTG LEQDMDEPFD M

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 54.39794
Match: 1bd3D
Description: Uracil PRTase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
uracil phosphoribosyltransferase activity 3.97944228585882 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 3.91023158228049 bayes_pls_golite062009
adenine phosphoribosyltransferase activity 3.07502596276449 bayes_pls_golite062009
hypoxanthine phosphoribosyltransferase activity 2.97347277288245 bayes_pls_golite062009
transferase activity 2.73727660668741 bayes_pls_golite062009
transferase activity, transferring pentosyl groups 2.53679639481311 bayes_pls_golite062009
catalytic activity 2.30431811394775 bayes_pls_golite062009
nucleobase binding 1.70525606708275 bayes_pls_golite062009
purine binding 1.24786927434743 bayes_pls_golite062009
transcription regulator activity 1.09798789282825 bayes_pls_golite062009
nucleic acid binding 1.07284130528063 bayes_pls_golite062009
ribose phosphate diphosphokinase activity 0.947697983706416 bayes_pls_golite062009
DNA binding 0.854593555814443 bayes_pls_golite062009
diphosphotransferase activity 0.749909396904601 bayes_pls_golite062009
binding 0.691442295634288 bayes_pls_golite062009
amidophosphoribosyltransferase activity 0.360901350940423 bayes_pls_golite062009
transcription factor activity 0.339219342075596 bayes_pls_golite062009
orotate phosphoribosyltransferase activity 0.148898393751978 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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