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Protein Overview: CE05540

General Information:
Name(s) found: CE05540 [WormBase]
Description(s) found:
Found 21 descriptions.
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  • WBGene00008386 status:Confirmed UniProt:G5EFC4 protein_id:CAB00029.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 755 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: embryonic cleavage [IMPLink to PubMed article]
    DNA repair [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    gastrulation with mouth forming first [IMPLink to PubMed article]
    cytokinesis [IMPLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVRVIIKGGV WKNTEDEILK AAIMKYGKNQ WSRIASLLHR KSAKQCKARW FEWLDPGIKK  60
   61 TEWSREEDEK LLHLAKLMPT QWRTIAPIVG RTSAQCLERY EHLLDEAQRK AEGLDEEATE 120
  121 TRKLKPGEID PTPETKPARP DPIDMDDDEL EMLSEARARL ANTQGKKAKR KARERQLSDA 180
  181 RRLASLQKRR EMRAAGLAFA RKFKPKRNQI DYSEEIPFEK HVPAGFHNPS EDRYVVEDAN 240
  241 QKAIEDHQKP RGREIEMEMR REDREKLKKR KEQGEADAVF NIKEKKRSKL VLPEPQISDR 300
  301 ELEQIVKIGH ASDSVRQYID GTATSGLLTD YTESARANAV AARTMRTPML KDTVQLELEN 360
  361 LMALQNTESA LKGGLNTPLH ESELGKGVLP TPKVAATPNT VLHAIAATPG TQSQFPGSTP 420
  421 GGFATPAGSV AATPFRDQMR INEEIAGSAL EQKASLKRAL ASLPTPKNDF EVVGPDDDEV 480
  481 EGAVEDESNQ DEDGWIEDAS ERAENKAKRN AENRVRNMKM RSQVIQRSLP KPTKVNEQAT 540
  541 RATNSSADDM VKAEMSKLLA WDVDNKPPSV IYSREELDAA ADLIKQEAES GPELNSLMWK 600
  601 VVEQCTSEII LSKDKFTRIA ILPREEQMKA LNDEFQMYRG WMNQRAKRAA KVEKKLRVKL 660
  661 GGYQAIHDKL CKKYQEVTTE IEMANIEKKT FERLGEHELK AINKRVGRLQ QEVTTQETRE 720
  721 KDLQKMYSKL SNKQWKLSQI EIHDAASTTS APITY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..165] PSI-BLAST 27.39794 c-Myb, DNA-binding domain
    2 View Details [166..331] FFAS03 1.05 crystal structure of the cytotoxic bacterial protein colicin B at 2.5 A resolution
    3 View Details [332..418] FFAS03 1.42 No description for 2fj7I was found.
    4 View Details [419..755] PSI-BLAST 21.39794 Heavy meromyosin subfragment

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  5.13863038737912 bayes_pls_golite062009
  • DNA binding
    		•  4.66369707598026 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.51452285155271 bayes_pls_golite062009
  • transcription factor activity
    		•  4.06706589695599 bayes_pls_golite062009
  • binding
    		•  3.02779747447702 bayes_pls_golite062009
  • RNA binding
    		•  2.55617811004485 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.41271657675151 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.26183812259792 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.91962622287073 bayes_pls_golite062009
  • transcription activator activity
    		•  1.77700860354597 bayes_pls_golite062009
  • transcription factor binding
    		•  1.40653841901929 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.14886080629275 bayes_pls_golite062009
  • chromatin binding
    		•  1.04132983826241 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.84983974758882 bayes_pls_golite062009
  • protein binding
    		•  0.830419844171551 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.810065362108106 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.2679415219517 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.25931464844298 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle