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View Structure Prediction Details

Protein: CE05540
Organism: Caenorhabditis elegans
Length: 755 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE05540.

Description E-value Query
Range
Subject
Range
gi|157747367 - gi|157747367|ref|XP_001668778.1| Hypothetical protein CBG12532 [Caenorhabditis briggsae AF16]
gi|187029160, gi... - gi|39595616|emb|CAE67118.1| Hypothetical protein CBG12532 [Caenorhabditis briggsae], gi|187029160|em...
251.0 [0..1] [755..1]

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Predicted Domain #1
Region A:
Residues: [1-165]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVRVIIKGGV WKNTEDEILK AAIMKYGKNQ WSRIASLLHR KSAKQCKARW FEWLDPGIKK  60
   61 TEWSREEDEK LLHLAKLMPT QWRTIAPIVG RTSAQCLERY EHLLDEAQRK AEGLDEEATE 120
  121 TRKLKPGEID PTPETKPARP DPIDMDDDEL EMLSEARARL ANTQG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.39794
Match: 1h88C
Description: c-Myb, DNA-binding domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.13863038737912 bayes_pls_golite062009
DNA binding 4.66369707598026 bayes_pls_golite062009
nucleic acid binding 4.51452285155271 bayes_pls_golite062009
transcription factor activity 4.06706589695599 bayes_pls_golite062009
binding 3.02779747447702 bayes_pls_golite062009
RNA binding 2.55617811004485 bayes_pls_golite062009
sequence-specific DNA binding 2.41271657675151 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.26183812259792 bayes_pls_golite062009
transcription repressor activity 1.91962622287073 bayes_pls_golite062009
transcription activator activity 1.77700860354597 bayes_pls_golite062009
transcription factor binding 1.40653841901929 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.14886080629275 bayes_pls_golite062009
chromatin binding 1.04132983826241 bayes_pls_golite062009
transcription cofactor activity 0.84983974758882 bayes_pls_golite062009
protein binding 0.830419844171551 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.810065362108106 bayes_pls_golite062009
transcription coactivator activity 0.2679415219517 bayes_pls_golite062009
transcription corepressor activity 0.25931464844298 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [166-331]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKAKRKARER QLSDARRLAS LQKRREMRAA GLAFARKFKP KRNQIDYSEE IPFEKHVPAG  60
   61 FHNPSEDRYV VEDANQKAIE DHQKPRGREI EMEMRREDRE KLKKRKEQGE ADAVFNIKEK 120
  121 KRSKLVLPEP QISDRELEQI VKIGHASDSV RQYIDGTATS GLLTDY

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.05
Match: 1rh1A
Description: crystal structure of the cytotoxic bacterial protein colicin B at 2.5 A resolution
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [332-418]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TESARANAVA ARTMRTPMLK DTVQLELENL MALQNTESAL KGGLNTPLHE SELGKGVLPT  60
   61 PKVAATPNTV LHAIAATPGT QSQFPGS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.42
Match: 2fj7I
Description: No description for 2fj7I was found.

Predicted Domain #4
Region A:
Residues: [419-755]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPGGFATPAG SVAATPFRDQ MRINEEIAGS ALEQKASLKR ALASLPTPKN DFEVVGPDDD  60
   61 EVEGAVEDES NQDEDGWIED ASERAENKAK RNAENRVRNM KMRSQVIQRS LPKPTKVNEQ 120
  121 ATRATNSSAD DMVKAEMSKL LAWDVDNKPP SVIYSREELD AAADLIKQEA ESGPELNSLM 180
  181 WKVVEQCTSE IILSKDKFTR IAILPREEQM KALNDEFQMY RGWMNQRAKR AAKVEKKLRV 240
  241 KLGGYQAIHD KLCKKYQEVT TEIEMANIEK KTFERLGEHE LKAINKRVGR LQQEVTTQET 300
  301 REKDLQKMYS KLSNKQWKLS QIEIHDAAST TSAPITY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.39794
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle